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Raw Materials
P2 Receptor
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP24140 | AF-353 hydrochloride New | 927887-18-1 |
AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively).
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BCP46868 | PIT New | 56583-49-4 |
Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems.
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BCP46785 | CE-224535 New | 724424-43-5 |
CE-224535 is a Purinergic receptor antagonist originated by Pfizer. Phase-II/III for Rheumatoid arthritis and Phase-II for Osteoarthritis were discontinued.
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BCP43056 | Eliapixant New | 1948229-21-7 |
Eliapixant is a purinoreceptor antagonist.
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BCP44190 | Lu AF27139 New | 2097117-06-9 |
Lu AF27139, a novel rodent-active and CNS-penetrant P2X7 receptor antagonist.
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BCP44118 | JNJ-54166060 New | 1627900-42-8 |
JNJ-54166060 is a potent P2X7 antagonist.
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BCP43716 | AZ10606120 dihydrochloride New | 607378-18-7 |
AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist that strongly inhibits tumor growth in B16-inoculated C57Bl/6 mice.
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BCP42041 | 2-Methylthioadenosine diphosphate trisodium salt New | 475193-31-8 |
2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13).
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BCP42040 | 2-MeS-ADP New | 34983-48-7 |
2-MeS-ADP is an agonist of P2Y1, P2Y12 and P2Y13 receptors.
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BCP40607 | MRS 2179 tetrasodium salt New | 1454889-37-2 |
MRS-2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors that inhibits the upregulation of NTPDase1 by ATPγS.
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