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P2 Receptor

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P2 Receptor

Chemical Structure Cat. No. Product Name CAS No.
AF-353 hydrochloride Chemical Structure
 BCP24140 AF-353 hydrochloride 927887-18-1
AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively).
PIT Chemical Structure
 BCP46868 PIT 56583-49-4
Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems.
CE-224535 Chemical Structure
 BCP46785 CE-224535 724424-43-5
CE-224535 is a Purinergic receptor antagonist originated by Pfizer. Phase-II/III for Rheumatoid arthritis and Phase-II for Osteoarthritis were discontinued.
Eliapixant Chemical Structure
 BCP43056 Eliapixant 1948229-21-7
Eliapixant is a purinoreceptor antagonist.
Lu AF27139 Chemical Structure
 BCP44190 Lu AF27139 2097117-06-9
Lu AF27139, a novel rodent-active and CNS-penetrant P2X7 receptor antagonist.
JNJ-54166060 Chemical Structure
 BCP44118 JNJ-54166060 1627900-42-8
JNJ-54166060 is a potent P2X7 antagonist.
AZ10606120 dihydrochloride Chemical Structure
 BCP43716 AZ10606120 dihydrochloride 607378-18-7
AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist that strongly inhibits tumor growth in B16-inoculated C57Bl/6 mice.
2-Methylthioadenosine diphosphate trisodium salt Chemical Structure
 BCP42041 2-Methylthioadenosine diphosphate trisodium salt 475193-31-8
2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13).
2-MeS-ADP Chemical Structure
 BCP42040 2-MeS-ADP 34983-48-7
2-MeS-ADP is an agonist of P2Y1, P2Y12 and P2Y13 receptors.
MRS 2179 tetrasodium salt Chemical Structure
 BCP40607 MRS 2179 tetrasodium salt 1454889-37-2
MRS-2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors that inhibits the upregulation of NTPDase1 by ATPγS.
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