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P2 Receptor

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P2 Receptor

Chemical Structure Cat. No. Product Name CAS No.
Selatogrel Chemical Structure
BCP49239 Selatogrel 1159500-34-1
Selatogrel is a reversible, selective, and potent antagonist of the platelet P2Y12 receptor.
AF353 Chemical Structure
BCP28391 AF353 865305-30-2
AF-353 is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3.
AF-353 hydrochloride Chemical Structure
BCP24140 AF-353 hydrochloride 927887-18-1
AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively).
PIT Chemical Structure
BCP46868 PIT 56583-49-4
Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems.
CE-224535 Chemical Structure
BCP46785 CE-224535 724424-43-5
CE-224535 is a Purinergic receptor antagonist originated by Pfizer. Phase-II/III for Rheumatoid arthritis and Phase-II for Osteoarthritis were discontinued.
Eliapixant Chemical Structure
BCP43056 Eliapixant 1948229-21-7
Eliapixant is a purinoreceptor antagonist.
Lu AF27139 Chemical Structure
BCP44190 Lu AF27139 2097117-06-9
Lu AF27139, a novel rodent-active and CNS-penetrant P2X7 receptor antagonist.
JNJ-54166060 Chemical Structure
BCP44118 JNJ-54166060 1627900-42-8
JNJ-54166060 is a potent P2X7 antagonist.
AZ10606120 dihydrochloride Chemical Structure
BCP43716 AZ10606120 dihydrochloride 607378-18-7
AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist that strongly inhibits tumor growth in B16-inoculated C57Bl/6 mice.
2-Methylthioadenosine diphosphate trisodium salt Chemical Structure
BCP42041 2-Methylthioadenosine diphosphate trisodium salt 475193-31-8
2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13).
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