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Autophagy

Chemical Structure Cat. No. Product Name CAS No.
DL-Selenomethionine Chemical Structure
 BCP24111 DL-Selenomethionine 1464-42-2
DL-Selenomethionine is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium.
SBP-7455 Chemical Structure
 BCP48924 SBP-7455 1884222-74-5
SBP-7455 is a potent, high affinity and orally active dual ULK1/ULK2 autophagy inhibitor with IC50s of 13 nM and 476 nM in the ADP-Glo assays, respectively. SBP-7455 potently inhibits ULK1/2 enzymatic activity and can be used for triple-negative breast cancer (TNBC) research.
CA77.1 Chemical Structure
 BCP48919 CA77.1 2412270-22-3
CA77.1 (CA) is a potent, brain-penetrant and orally active activator of chaperone-mediated autophagy (CMA) for the treament of Alzheimer's disease (AD).
Heparin calcium Chemical Structure
 BCP25407 Heparin calcium 37270-89-6
Heparin calcium is an injection form of heparin, a sulfated polysaccharide that has been used as a life-saving anticoagulant in clinics well before its detailed structure was known.
LYN-1604 dihydrochloride Chemical Structure
 BCP33963 LYN-1604 dihydrochloride 2310109-38-5
LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC).
FMK 9a Chemical Structure
 BCP48038 FMK 9a 1955550-51-2
FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay.
PTC-209 hydrobromide Chemical Structure
 BCP47397 PTC-209 hydrobromide 1217022-63-3
PTC-209 Hydrobromide is a novel potent BMI1-inhibitor, modulating the RE1.
P62-mediated mitophagy inducer Chemical Structure
 BCP47283 P62-mediated mitophagy inducer 1809031-84-2
P62-mediated mitophagy inducer is a regulator of mitophagy .
AGN 196996 Chemical Structure
 BCP46996 AGN 196996 958295-17-5
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).
Carprofen Chemical Structure
 BCP10435 Carprofen 53716-49-7
Carprofen is a nonsteroid anti-inflammatory agent, acts as a multi-target FAAH/COX inhibitor, with IC50s of 3.9 μM, 22.3 μM and 78.6 μM for COX-2, COX-1 and FAAH, respectively.
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