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HDAC

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HDAC

Chemical Structure Cat. No. Product Name CAS No.
Belinostat Chemical Structure
 BCP24610 Belinostat 866323-14-0
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
Snail/HDAC-IN-1 Chemical Structure
 BCP48514 Snail/HDAC-IN-1 2415281-52-4
Snail/HDAC-IN-1 is a potent Snail/HDAC dual target inhibitor.
KA2507 Chemical Structure
 BCP46450 KA2507 1636894-46-6
KA2507 is a potent and selective HDAC6 inibitor with an IC50 of 2.5nM.
Quisinostat HCl Chemical Structure
 BCP44306 Quisinostat HCl 1083078-98-1
Quisinostat, also known as JNJ-26481585, is an orally bioavailable, second-generation, hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
Pracinostat Dihydrochloride Chemical Structure
 BCP43352 Pracinostat Dihydrochloride 929016-98-8
Pracinostat, also known as SB939, is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity.
RGFP966 Chemical Structure
 BCP42941 RGFP966 1396841-57-8
RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM in cell-free assay, exhibits > 200-fold selectivity over other HDAC.
Resminostat hydrochloride Chemical Structure
 BCP39644 Resminostat hydrochloride 1187075-34-8
Resminostat HCl is a potent inhibitor of HDAC1/3/6.
SKLB-23bb Chemical Structure
 BCP37616 SKLB-23bb 1815580-06-3
SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability.
Crotonoside Chemical Structure
 BCP34471 Crotonoside 1818-71-9
Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the treatment of AML.
Sinapic acid Chemical Structure
 BCP25316 Sinapic acid 530-59-6
Sinapic acid is found in american cranberry. Sinapic acid is a common constituent of plants and fruit.
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