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Wnt

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Wnt

Chemical Structure Cat. No. Product Name CAS No.
HLY78 Chemical Structure
BCP45530 HLY78 854847-61-3
HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction.
FIDAS-3 Chemical Structure
BCP45452 FIDAS-3 1266684-01-8
FIDAS-3 is a stilbene derivative and is a potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A).
Dalosirvat Chemical Structure
BCP44837 Dalosirvat 1360540-81-3
Dalosirvat is a topical Wnt pathway activator for the treatment of androgenetic alopecia (AGA).
FOXY-5 Chemical Structure
BCP43701 FOXY-5 881188-51-8
FOXY-5 is a Wnt5a peptide mimetic. It has been undergoing clinical trials for the treatment of prostate cancer, colorectal cancer, metastatic colon cancer, metastatic breast cancer, and metastatic prostate cancer.
Heparitin, sulfate Chemical Structure
BCP43695 Heparitin, sulfate 9050-30-0
Heparan sulfate, a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix.
Adavivint HCl Chemical Structure
BCP42884 Adavivint HCl AdavivintHCl
Adavivint is a small-molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee.
IWP-O1 Chemical Structure
BCP41115 IWP-O1 2074607-48-8
IWP-O1 is a potent porcupine inhibitor that blocks Wnt signaling in L-Wnt-STF cells with EC50 value of 80 pM. IWP-O1 can affect differentiation of hESC.
PRI-724 Chemical Structure
BCP39699 PRI-724 1198780-43-6
PRI-724, an isomer or enantiomer of ICG-001, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.
Pyrvinium pamoate Chemical Structure
BCP38435 Pyrvinium pamoate 3546-41-6
Pyrvinium pamoate is a naphthoic acid. It has a role as an anticoronaviral agent.
G244-LM Chemical Structure
BCP37837 G244-LM 1563007-08-8
G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization.
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