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PI3K

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PI3K

Chemical Structure Cat. No. Product Name CAS No.
SRX3177 Chemical Structure
 BCP48567 SRX3177 2241237-51-2
SRX3177 is a novel potent triple action inhibitor, targeting BRD, PI3K, and CDK.
PI3K/mTOR Inhibitor-2 Chemical Structure
 BCP48401 PI3K/mTOR Inhibitor-2 1848242-58-9
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor.
AZD-3458 Chemical Structure
 BCP47242 AZD-3458 2132961-46-5
AZD3458 is a potent and remarkably selective PI3Kγ inhibitor for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ.
Disitertide Chemical Structure
 BCP46789 Disitertide 272105-42-7
Disitertide is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide is also a PI3K inhibitor and an apoptosis inducer.
IHMT-PI3Kδ-372 Chemical Structure
 BCP46775 IHMT-PI3Kδ-372 2429889-62-1
IHMT-PI3Kδ-372 is a potent and selective phosphatidylinositol 3-kinase δ (PI3Kδ) inhibitor with an IC50 of 14 nM in the biochemical assay.
Gilmelisib Chemical Structure
 BCP46378 Gilmelisib 1845777-61-8
Gilmelisib is a PI3K inhibitor and antineoplastic.
GSK251 Chemical Structure
 BCP46226 GSK251 2125968-05-8
GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode.
ETP-45658 Chemical Structure
 BCP45165 ETP-45658 1198357-79-7
ETP-45658 is a PI3-kinase inhibitor, also ihibiting DNA-PK and mTOR.
GS-9901 Chemical Structure
 BCP44115 GS-9901 1640247-87-5
GS-9901 is a potent, orally active and highly selective inhibitor of PI3Kδ (PI3Kdelta IC50 = 1.0nM, HWB delta EC50 = 1.5 nM; CLpr hHep = 0.05 L/h/kg.).
Panulisib Chemical Structure
 BCP44105 Panulisib 1356033-60-7
Panulisib is an orally bioavailable inhibitor of phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR), activin receptor-like kinase 1 (ALK-1) and DNA-dependent protein kinase (DNA-PK), with potential anti-angiogenic and antineoplastic activities.
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