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NLR

Chemical Structure Cat. No. Product Name CAS No.
QS-21 Chemical Structure
 BCP49573 QS-21 141256-04-4
QS21 is a purified, natural saponin isolated from the soapbark tree Quillaja saponaria Molina with potential immunoadjuvant activity. When co-administered with vaccine peptides, QS21 may increase total antitumoral vaccine-specific antibody responses and cytotoxic T-cell responses.
Selnoflast Chemical Structure
 BCP49321 Selnoflast 2260969-36-4
Selnoflast is a NLRP3 inhibitor.
Emlenoflast Chemical Structure
 BCP35616 Emlenoflast 1995067-59-8
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
MCC7840 sodium Chemical Structure
 BCP48756 MCC7840 sodium 2380032-29-9
MCC7840 sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. MCC7840 sodium can be used for the research of inflammatory diseases.
BMS-986299 Chemical Structure
 BCP44085 BMS-986299 2242952-69-6
BMS-986299 is a First-In-Class NLRP3 Innate Agonist with Potent Antitumor Activity.
Dapansutrile Chemical Structure
 BCP36209 Dapansutrile 54863-37-5
Dapansutrile is a potent, selective and orally active inhibitor of NLRP3 inflammasome. Anti-inflammatory, analgesic activity.
NOD-IN-1 Chemical Structure
 BCP24808 NOD-IN-1 132819-92-2
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.
Troxerutin Chemical Structure
 BCP13421 Troxerutin 7085-55-4
Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.
Arglabin Chemical Structure
 BCP09930 Arglabin 84692-91-1
Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella; anticancer natural compound.
Nodinitib-1 Chemical Structure
 BCP20383 Nodinitib-1 799264-47-4
Afuresertib is an orally available, ATP-competitive, pan-AKT inhibitor with Ki of 0.08, 2 and 2.6 nM against AKT1, AKT2 and AKT3, respectively.
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