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nAChR

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nAChR

Chemical Structure Cat. No. Product Name CAS No.
Anagyrin Chemical Structure
 BCP44368 Anagyrin 486-89-5
Anagyrine is an alkaloid that has been found in L. albus and has nematocidal and anticancer activities.
ABT-418 hydrochloride Chemical Structure
 BCP38433 ABT-418 hydrochloride 147388-83-8
ABT-418 hydrochloride is a neuronal nicotinic acetylcholine receptor agonist.
4BP-TQS Chemical Structure
 BCP37825 4BP-TQS 360791-49-7
4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs).
PSEM 89S TFA Chemical Structure
 BCP35173 PSEM 89S TFA 1336913-03-1
PSEM 89S TFA is a selective and brain penetrant agonists for the resulting ion channels. PSEM 89S TFA is orthogonally selective for Q79G and L141F, respectively.
CCMI Chemical Structure
 BCP35052 CCMI 917837-54-8
CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction.
nAChR agonist 1 Chemical Structure
 BCP33344 nAChR agonist 1 1394371-75-5
nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR).
Facinicline hydrochloride Chemical Structure
 BCP33359 Facinicline hydrochloride 677305-02-1
PNU-282987 S enantiomer free base Chemical Structure
 BCP25435 PNU-282987 S enantiomer free base 737727-12-7
PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).
SUVN-911 Chemical Structure
 BCP32917 SUVN-911 2414674-71-6
SUVN-911 is a Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.
ZSET-1446 Chemical Structure
 BCP33073 ZSET-1446 887603-94-3
ZSET1446(ST-101) is a novel cognitive enhancer that significantly improves learning deficits in various types of Alzheimer disease (AD) models.
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