Home   >  
Protease/Metabolic Enzyme
  >  
E1 E2 E3 Enzyme

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

E1 E2 E3 Enzyme

Chemical Structure Cat. No. Product Name CAS No.
Ubiquitination-IN-1 Chemical Structure
 BCP46940 Ubiquitination-IN-1 1819330-15-8
Ubiquitination-IN-1 is a ubiquitination and Cksl-Skp2 protein-protein interaction (IC50 =0.17 μM) inhibitor.
M435-1279 Chemical Structure
 BCP46473 M435-1279 1359431-16-5
M435-1279 is a UBE2T inhibitor.
NSC697923 Chemical Structure
 BCP45754 NSC697923 343351-67-7
NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A.
NSC232003 Chemical Structure
 BCP44628 NSC232003 1905453-18-0
NAcM-OPT Chemical Structure
 BCP35044 NAcM-OPT 2089293-61-6
NAcM-OPT is a specific, reversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 79 nM
CC-92480 Chemical Structure
 BCP32805 CC-92480 2259648-80-9
CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity.
DKM 2-93 Chemical Structure
 BCP32598 DKM 2-93 65836-72-8
DKM 2-93 is a relatively selective inhibitor of UBA5 with an IC50 of 430 μM.
COH000 Chemical Structure
 BCP31057 COH000 1534358-79-6
COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro.
Thalidomide Chemical Structure
 BCP19772 Thalidomide 50-35-1
Thalidomide is initially promoted as a sedative, inhibits ereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.
TAME Chemical Structure
 BCP02395 TAME 901-47-3
Tosyl-L-Arginine Methyl Ester (TAME) is an APC inhibitor.
123下一页共 25 条记录 1 / 3 页 
0086-13720134139