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MEK/ERK

Chemical Structure Cat. No. Product Name CAS No.
ONC-201 Dihydrochloride Chemical Structure
BCP46830 ONC-201 Dihydrochloride 1638178-82-1
ONC-201, also known as TIC10, is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.
PD184161 Chemical Structure
BCP46466 PD184161 212631-67-9
PD184161 is an orally active MEK inhibitor. PD184161 inhibits MEK activity (IC50=10-100 nM) in a time- and concentration-dependent manner. PD184161 inhibits cell proliferation and induces apoptosis. PD184161 produces depressive-like behavior.
Rineterkib hydrochloride Chemical Structure
BCP43938 Rineterkib hydrochloride 1715025-34-5
Rineterkib is a RAF and ERK1/2 inhibitor which has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models.
BAY-885 Chemical Structure
BCP34724 BAY-885 2307249-33-6
BAY-885 is a highly potent and selective ERK5 inhibitor.
Rineterkib Chemical Structure
BCP38204 Rineterkib 1715025-32-3
Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway.
trans-Zeatin Hydrochloride Chemical Structure
BCP36686 trans-Zeatin Hydrochloride 6025-81-6
trans-Zeatin Hydrochloride can be used in biological study and therapeutic use for plant-growth factors as cell-proliferating agents for promotion of wound healing.
Urolithin B Chemical Structure
BCP35736 Urolithin B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
ERK5-IN-2 Chemical Structure
BCP32587 ERK5-IN-2 1888305-96-1
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.
Longdaysin Chemical Structure
BCP32583 Longdaysin 1353867-91-0
Longdaysin is a novel inhibitor of CK1, ERK2, and CDK7 kinases.
ASTX-029 Chemical Structure
BCP32082 ASTX-029 2095719-92-7
ASTX029 is selective Inhibitor of Extracellular Signal-Related Protein Kinases 1 and 2 (ERK 1/2)
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