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STING

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STING

Chemical Structure Cat. No. Product Name CAS No.
E7766 Chemical Structure
 BCP40761 E7766 2242635-02-3
E7766 is a STING agonist.
ChX710 Chemical Structure
 BCP39194 ChX710 2438721-44-7
ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF).
MSA-2 Chemical Structure
 BCP35448 MSA-2 129425-81-6
MSA-2 is an orally available non-nucleotide STING agonist, with EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.
SR-717 free acid Chemical Structure
 BCP35922 SR-717 free acid 2375420-34-9
SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 free acid is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity.
SR-717 Chemical Structure
 BCP35417 SR-717 2375421-09-1
SR-717 is an agonist of stimulator of interferon genes STING for treating cancer.
Omaveloxolone Chemical Structure
 BCP28609 Omaveloxolone 1474034-05-3
Omaveloxolone, also known as RTA-408, is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity.
diABZI STING agonist-1 Chemical Structure
 BCP33343 diABZI STING agonist-1 2138299-33-7
diABZI STING agonist-1 is a potent non-nucleotide STING agonist and has tremendous potential to improve treatment of cancer in humans.
STING agonist-1 Chemical Structure
 BCP33022 STING agonist-1 702662-50-8
STING agonist-1 (G10) is a human-specific STING agonist, triggering IRF3/IFN-associated transcription in human fibroblasts.
ADUS100 sodium Chemical Structure
 BCP29778 ADUS100 sodium 1638750-95-4
ADU-S100 is a Cyclic Dinucleotide Agonist of STING (Stimulator of Interferon Genes) pathway.
diABZI STING agonist-1 Chemical Structure
 BCP29981 diABZI STING agonist-1 2138498-18-5
diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
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