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Chemical Structure Cat. No. Product Name CAS No.
A-769662 Chemical Structure
BCP01873 A-769662 844499-71-4
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers.
Purmorphamine Chemical Structure
BCP03687 Purmorphamine 483367-10-8
Purmorphamine is an activator of Smoothened, and blocks BODIPY-cyclopamine binding to Smo with IC50 of appr 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM.
Cabazitaxel Chemical Structure
BCP27641 Cabazitaxel 183133-96-2
A novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor.
VX-765 Chemical Structure
BCP02893 VX-765 273404-37-8
VX-765 is an orally absorbed prodrug of VRT-043198, which exhibits potent inhibition against ICE/caspase-1 and caspase-4 with Ki of 0.8 nM and less than 0.6 nM, respectively.
Nicotinamide Riboside Chemical Structure
BCP06938 Nicotinamide Riboside 1341-23-7
Nicotinamide riboside is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
Momelotinib Chemical Structure
BCP02328 Momelotinib 1056634-68-4
Momelotinib, also known as CYT387, is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively. The inhibitor is significantly less active towards other kinases, including JAK3 (IC50 = 0.16 μM). As of 2011, CYT387 is being developed as a drug for myelofibrosis and currently undergoes Phase I/II clinical trials. Additional potential treatment indications for CYT387 include other myeloproliferative neoplasms, cancer (solid and liquid tumors) and inflammatory conditions.
Bevacizumab Chemical Structure
BCP07998 Bevacizumab 216974-75-3
Bevacizumab is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor A (VEGF-A).
Delamanid Chemical Structure
BCP07838 Delamanid 681492-22-8
Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex.
GS441524 Chemical Structure
BCP35590 GS441524 1191237-69-0
GS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir]. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.
D-Luciferin k Salt Chemical Structure
BCP08298 D-Luciferin k Salt 115144-35-9
D-Luciferin potassium salt is the substrate of luciferases that catalyze the production of light in bioluminescent insects.
3,4-Diaminofurazan Chemical Structure
BCP00227 3,4-Diaminofurazan 17220-38-1
3,4-Diaminofurazan is a building block used to prepare magnesium and zinc alkynylated salicylaldehyde-diamine Schiff base complexes.
APR-246 Chemical Structure
BCP20294 APR-246 5291-32-7
APR-246 restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1Met also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.
Temsirolimus Chemical Structure
BCP25281 Temsirolimus 162635-04-3
Temsirolimus (CCI-779, NSC 683864) is a specific mTOR inhibitor with IC50 of 1.76 μM in a cell-free assay.
Vortioxetine Chemical Structure
BCP05996 Vortioxetine 508233-74-7
Vortioxetine (Lu AA21004) is an investigational novel antidepressant with multimodal activity that functions as a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, 5-HT1B receptor partial agonist, 5-HT1A receptor agonist and inhibitor of the 5-HT transporter in vitro.
Favipiravir Chemical Structure
BCP02422 Favipiravir 259793-96-9
Favipiravir, also known as T705, is a RNA-directed RNA polymerase NS5B inhibitor
Repotrectinib Chemical Structure
BCP19778 Repotrectinib 1802220-02-5
TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 5.3 nM, 1.01 nM, 1.26 nM and 1.08 nM for SRC, WT ALK, ALK G1202R and ALK L1196M, respectively.
Adavosertib Chemical Structure
BCP01928 Adavosertib 955365-80-7
MK-1775 is a potent and selective Wee1 kinase inhibitor with an IC50 of 5.2 nM.
LOXO-195 Chemical Structure
BCP20662 LOXO-195 2097002-61-2
LOXO-195 is a next-generation TRK kinase (TKI) inhibitor, with IC50s of 0.6±0.1 nM, <2.5 nM for TRKA and TRKC respectively.
D-glucono-1,4-lactone Chemical Structure
BCP17475 D-glucono-1,4-lactone 1198-69-2
D-glucono-1,4-lactone is a gluconolactone derived form D-gluconic acid.
Resiquimod Chemical Structure
BCP09103 Resiquimod 144875-48-9
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