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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
BIO-32546 Chemical Structure
 BCP28835 BIO-32546 1548743-66-3
BIO-32546 is an autotaxin (ATX) modulator, extracted from the patent US20170158687A1.
Cytochrome P450 14a-demethylase inhibitor 1J Chemical Structure
 BCP23782 Cytochrome P450 14a-demethylase inhibitor 1J 1155361-08-2
Cytochrome P450 14a-demethylase inhibitor 1J is an inhibitor of CYP isoenzymes and an antifungal agent.
AVN-944 Chemical Structure
 BCP23877 AVN-944 297730-17-7
AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism, DNA replication, apoptosis and cell cycle control. AVN944 has been associated with cancer cell death in clinical trials. It is being investigated for the treatment of patients with advanced hematologic malignancies.
Tunodafil Chemical Structure
 BCP23996 Tunodafil 804518-63-6
Tunodafil is a novel phosphodiesterase 5 (PDE5) inhibitor.
ITMN 4077 Chemical Structure
 BCP24014 ITMN 4077 790305-05-4
ITMN 4077 is a macrocyclic inhibitor against Hepatitis C Virus (HCV) NS3 protease (EC50: 2131 nM).
Ethoxzolamide Chemical Structure
 BCP24088 Ethoxzolamide 452-35-7
Ethoxzolamide is a carbonic anhydrase inhibitor with Ki of 1 nM.
Voxilaprevir Chemical Structure
 BCP24118 Voxilaprevir 1535212-07-7
Voxilaprevir (GS-9857) is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection.
Razaxaban Chemical Structure
 BCP24153 Razaxaban 218298-21-6
Razaxaban is a highly potent, selective, and orally bioavailable factor Xa (FXa) inhibitor with Ki of o.19 nM, >5,000-fold selectivity over a series of related serine proteases.
Fexarine Chemical Structure
 BCP24188 Fexarine 574013-67-5
Fexarine is a potent, selective farnesoid X receptor agonist.
GSK9772 Chemical Structure
 BCP24282 GSK9772 928035-84-1
GSK9772 is a novel potent transrepression-selective liver X receptor modulator with anti-inflammatory activity.
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