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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
L-778123 Chemical Structure
BCP44918 L-778123 183499-57-2
L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation.
VAS3947 Chemical Structure
BCP44868 VAS3947 869853-70-3
VAS3947 is a selective inhibitor of NADPH oxidase activity in low micromolar concentrations, interfering neither with ROS detection nor with XOD or eNOS activities.
GS-CA-1 Chemical Structure
BCP44793 GS-CA-1 2189684-45-3
GS-CA1 is a potent HIV capsid inhibitor for HIV inhibition.
Tovinontrine Chemical Structure
BCP44778 Tovinontrine 2062661-53-2
Tovinontrine (IMR-687) is a highly potent and selective phosphodiesterase-9 (PDE9) inhibitor specifically for the treatment of sickle cell disease. IC50s are 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively.
Firibastat Chemical Structure
BCP44770 Firibastat 648927-86-0
Firibastat, also known as QGC-001 and RB-150, is a glutamyl aminopeptidase antagonist potentially for the treatment of hypertension.
NCT-505 Chemical Structure
BCP44645 NCT-505 2231079-74-4
NCT-505 is an Orally Bioavailable aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitor with Potent Cellular Activity (IC50 = 7 nM).
RV01 Chemical Structure
BCP44644 RV01 1016897-10-1
RV01 is an analogue of resveratrol.
Brecanavir Chemical Structure
BCP44630 Brecanavir 313682-08-5
Brecanavir is a tyrosyl-based arylsulfonamide inhibitor of human immunodeficiency virus (HIV) protease.
NSC232003 Chemical Structure
BCP44628 NSC232003 1905453-18-0
TAN 1364B Chemical Structure
BCP44603 TAN 1364B 154639-24-4
TAN 1364B is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of RK-682. TAN 1364B inhibits the activity of the PTPs LMW-PTP, CDC25B, and PTP1B, but the inhibitory activity against LMW-PTP and CDC25B is blocked in the presence of magnesium.
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