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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
SI113 Chemical Structure
BCP49628 SI113 1392816-46-4
SI113 is a SGK1 inhibitor, with an IC50 of 600 nM. SI113 induces autophagy.
5-LOX-IN-1 Chemical Structure
BCP49611 5-LOX-IN-1 55040-82-9
5-LOX-IN-1 is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM.
hCAIX-IN-5 Chemical Structure
BCP49610 hCAIX-IN-5 2451479-57-3
hCAIX-IN-5 is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively.
Lonodelestat Chemical Structure
BCP49598 Lonodelestat 906547-89-5
Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE).
BAY-179 Chemical Structure
BCP49597 BAY-179 2764880-87-5
BAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor.
Cbl-b-IN-3 Chemical Structure
BCP49568 Cbl-b-IN-3 2573775-59-2
Cbl-b-IN-3 is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM.
ASC-42 Chemical Structure
BCP49481 ASC-42 ASC-42
ASC 42 is a selective, non-steroidal, potent Farnesoid X Receptor (FXR) agonist.
MET-642 Chemical Structure
BCP49382 MET-642 MET-642
MET 642 is a small molecule farnesoid X receptor (FXR) agonist.
MK-2060 Chemical Structure
BCP49317 MK-2060 MK-2060
MK-2060 is a novel inhibitor of Factor XI being investigated for the prevention of thrombosis in patients with end-stage renal disease (ESRD).
GNE-617 hydrochloride Chemical Structure
BCP49280 GNE-617 hydrochloride 2070014-99-0
GNE-617 hydrochloride is a specific NAMPT inhibitor that inhibits the biochemical activity of NAMPT with an IC50 of 5 nM and exhibits efficacy in xenograft models of cancer.
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