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p38 MAPK

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p38 MAPK

Chemical Structure Cat. No. Product Name CAS No.
FR 167653 sulfate Chemical Structure
 BCP25927 FR 167653 sulfate 158876-66-5
FR-167653 is a selective p38 MAPK inhibitor.
p38-α MAPK inhibitor 1 Chemical Structure
 BCP48493 p38-α MAPK inhibitor 1 443913-15-3
p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.
SM-7368 Chemical Structure
 BCP46452 SM-7368 380623-76-7
SM-7368 inhibits TNF-alpha-induced MMP-9 upregulation in a concentration-dependent manner. SM-7368 strongly inhibits the TNF-alpha-induced invasion of HT1080 human fibrosarcoma cell line.
SB-747651A Chemical Structure
 BCP46274 SB-747651A 607372-46-3
SB-747651A is a specific mitogen- and stress-activated kinase 1 (MSK1) inhibitor. SB-747651A can be used for the research of inflammation.
SB-747651A dihydrochloride Chemical Structure
 BCP46273 SB-747651A dihydrochloride 1781882-72-1
SB-747651A dihydrochloride is a potent MSK1 inhibitor; also inhibiting other AGC group kinases.
PF-05381941 Chemical Structure
 BCP45842 PF-05381941 1474022-02-0
PF-05381941 is a novel potent dual TAK1/p38a inhibitor.
AZD7624 Chemical Structure
 BCP37429 AZD7624 1095004-78-6
AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
MW-150 Chemical Structure
 BCP34874 MW-150 1628502-91-9
MW-150 is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM
SB 203580 hydrochloride Chemical Structure
 BCP29070 SB 203580 hydrochloride 869185-85-3
SB 203580 hydrochloride is a widely used p38 MAPK inhibitor. SB 203580 hydrochloride (RWJ 64809 hydrochloride) inhibits SAPK2a/p38 and SAPK2b/p38β2, with IC50s of 50 nM and 500 nM, respectively. LCK, GSK3β and PKBα are also inhibited by SB 203580 hydrochloride, but the IC50s are 100-500-fold higher than that for SAPK2a/p38.
LY2322600 Chemical Structure
 BCP27665 LY2322600 862505-01-9
LY2228820 is a novel and potent p38MAPK inhibitor.
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