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Hormone Pathay

Chemical Structure Cat. No. Product Name CAS No.
ARV-471 Chemical Structure
BCP45881 ARV-471 2229711-08-2
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader.
ML 145 Chemical Structure
BCP45167 ML 145 1164500-72-4
ML 145 is a selective antagonist for the GPR35 orphan receptor GPCR (IC50 = 20.1 nM). Over 1000-fold more selective for GPR35 compared to GPR55 antagonists.
Difelikefalin TFA Chemical Structure
BCP44865 Difelikefalin TFA 2742623-88-5
Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM).
Amcenestrant Chemical Structure
BCP38455 Amcenestrant 2114339-57-8
Amcenestrant (SAR439859) is an orally available and nonsteroidal selective estrogen receptor degrader (SERD) with potential antineoplastic activity. SAR439859 is a potent estrogen receptor (ER) antagonist with EC50 of 0.2 nM for ERα degradation.
U-54494A Chemical Structure
BCP44497 U-54494A 92953-41-8
U-54494A is a κ-opioid agonist and a potential NMDA antagonist. U-54494A hydrochloride is used as an anticonvulsant.
Difelikefalin HCl Chemical Structure
BCP44189 Difelikefalin HCl 2413256-25-2
Difelikefalin is a novel and potent kappa opioid receptor agonist.
Giredestrant tartrate Chemical Structure
BCP43932 Giredestrant tartrate 2407529-33-1
Giredestrant, also known as GDC-9545 and RG6171, is a SERD.
SCO-267 Chemical Structure
BCP41795 SCO-267 1656261-09-4
SCO-267 is a novel GPR40 full agonist, improving liver parameters in a mouse model of nonalcoholic fatty liver disease without affecting glucose or body weight.
AS1269574 Chemical Structure
BCP43461 AS1269574 330981-72-1
AS-1269574 is a selective, orally available GPR119 agonist with EC50 of 2.5 uM in cell-based cAMP assays.
TAK041 Chemical Structure
BCP43188 TAK041 1929519-13-0
TAK-041 is a novel Potent and Selective GPR139 Agonist for the Treatment of Negative Symptoms Associated with Schizophrenia.
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