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PROTAC

Chemical Structure Cat. No. Product Name CAS No.
Mal-PEG1-PNP-carbonate Chemical Structure
 BCP24746 Mal-PEG1-PNP-carbonate 1345681-74-4
Mal-PEG1-PNP-carbonate is a amine-reactive compound.
Cyanine5 amine Chemical Structure
 BCP24921 Cyanine5 amine 1807589-58-7
Cyanine5 amine is a reactive dye which contains amino group, an analog of Cy5® amine. This reagent can be coupled with a variety of activated esters and other electrophilic reagents. For example, this amine can be coupled with EDC-activated carboxylic groups.
Thalidomide-NH-PEG1-NH2 hydrochloride Chemical Structure
 BCP48963 Thalidomide-NH-PEG1-NH2 hydrochloride 2154342-56-8
Thalidomide-NH-PEG1-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker.
Pomalidomide-piperazine HCl Chemical Structure
 BCP48873 Pomalidomide-piperazine HCl 2230956-83-7
Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand substituted with piperazine. Ready for conjugation to a target protein ligand to form PROTACs containing Pomalidomide as cereblon ligand.
Lenalidomide hemihydrate Chemical Structure
 BCP25399 Lenalidomide hemihydrate 847871-99-2
Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.
Azido-PEG3-Amine Chemical Structure
 BCP25832 Azido-PEG3-Amine 134179-38-7
Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3.
Bis-PEG5-acid Chemical Structure
 BCP25833 Bis-PEG5-acid 439114-13-3
Bis-PEG5-acid is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker.
DSPE-PEG(2000)-amine Chemical Structure
 BCP25996 DSPE-PEG(2000)-amine 474922-26-4
DSPE-PEG(2000) Amine is a functionalized polyethylene glycol (PEG) conjugated lipid.
(S,R,S)-AHPC Chemical Structure
 BCP33414 (S,R,S)-AHPC 2055344-67-5
(S,R,S)-AHPC is a VHL ligand that used in the recruitment of the VHL protein.
VH 101, acid Chemical Structure
 BCP34105 VH 101, acid 2408341-97-7
VH 101, acid is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with carboxylic acid handle at the benzylic position ready for conjugation to a target protein ligand.
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