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Chemical Structure Cat. No. Product Name CAS No.
TL 12-186 Chemical Structure
BCP49644 TL 12-186 2250025-88-6
TL12-186 is a Cereblon-dependent kinase degrader that degrades CDK, BTK, FLT3, Aurora and other kinases.TL12-186 inhibits CDK2/cyclin A and CDK9/cyclin T1 with IC50s of 73 and 55 nM, respectively.
Tos-PEG3-alcohol Chemical Structure
BCP49618 Tos-PEG3-alcohol 77544-68-4
Tos-PEG3 is a polyethylene glycol (PEG)-based PROTAC linker. Tos-PEG3 can be used in the synthesis of a series of PROTACs.
Polyethyleneglycolbis(methanesulfonate) Chemical Structure
BCP49583 Polyethyleneglycolbis(methanesulfonate) 52410-74-9
Ethylene dimethanesulfonate is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs.
Poly(ethylene glycol) bisazide Chemical Structure
BCP49582 Poly(ethylene glycol) bisazide 82055-94-5
Pentaerythritol propoxylate may be used as a precipitant in reservoir solution for the crystallization of Phosphate Transporter(PiPT) and Aggregation Suppressing Protein A(AgsA).
Pentaethylene Glycol Monomethyl Ether Chemical Structure
BCP28370 Pentaethylene Glycol Monomethyl Ether 23778-52-1
Pentaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Mal-PEG1-PNP-carbonate Chemical Structure
BCP24746 Mal-PEG1-PNP-carbonate 1345681-74-4
Mal-PEG1-PNP-carbonate is a amine-reactive compound.
Cyanine5 amine Chemical Structure
BCP24921 Cyanine5 amine 1807589-58-7
Cyanine5 amine is a reactive dye which contains amino group, an analog of Cy5® amine. This reagent can be coupled with a variety of activated esters and other electrophilic reagents. For example, this amine can be coupled with EDC-activated carboxylic groups.
Thalidomide-NH-PEG1-NH2 hydrochloride Chemical Structure
BCP48963 Thalidomide-NH-PEG1-NH2 hydrochloride 2154342-56-8
Thalidomide-NH-PEG1-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker.
Pomalidomide-piperazine HCl Chemical Structure
BCP48873 Pomalidomide-piperazine HCl 2230956-83-7
Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand substituted with piperazine. Ready for conjugation to a target protein ligand to form PROTACs containing Pomalidomide as cereblon ligand.
Lenalidomide hemihydrate Chemical Structure
BCP25399 Lenalidomide hemihydrate 847871-99-2
Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.
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