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Nature products
Antibodies
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Catalysts
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Intermediate
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Raw Materials
mTOR
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP46023 | NV-5138 hydrochloride New | NV5138HCl |
NV-5138 (hydrochloride), a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 (hydrochloride) is used for antidepressant studies.
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BCP44105 | Panulisib New | 1356033-60-7 |
Panulisib is an orally bioavailable inhibitor of phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR), activin receptor-like kinase 1 (ALK-1) and DNA-dependent protein kinase (DNA-PK), with potential anti-angiogenic and antineoplastic activities.
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BCP25153 | RapaLink-1 New | 1887095-82-0 |
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors.
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BCP39080 | NV-5138 New | 2095886-80-7 |
NV-5138, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2.
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BCP38015 | MT 63-78 New | 1179347-65-9 |
MT 63-78 is a direct activator of AMPK, and an inhibitor of prostate cancer growth by blocking lipogenesis.
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BCP36715 | MTI-31 New | 1567915-38-1 |
MTI-31 is a novel potent, selective mTORC1/mTORC2 inhibitor with Kd of 0.2 nM (mTOR), displays >5,000-fold selectivity over PIK3CA, PIK3CB and PIK3G.
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BCP36117 | PI-103 Hydrochloride New | 371935-79-4 |
PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.
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BCP33282 | Rapalink-1 New | Rapalink-1 |
RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin with MLN0128 (a second-generation mTOR kinase inhibitor) by an inert chemical linker.
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BCP25958 | AZD8055 Fumaric acid New | 1201799-05-4 |
AZD-8055 is a novel ATP-competitive inhibitor of mTOR kinase with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2.
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BCP25959 | AZD8055 D(-)-Tartaric Acid New | 1201799-04-3 |
AZD-8055 is a novel ATP-competitive inhibitor of mTOR kinase with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2.
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