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mTOR

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mTOR

Chemical Structure Cat. No. Product Name CAS No.
AZD 3147 Chemical Structure
 BCP24240 AZD 3147 1101810-02-9
AZD3147 is a potent, orally active, selective dual inhibitor of mTORC1 and mTORC2 with an IC50 value of 1.5 nM. AZD3147 also has a selective effect on PI3K.
RMC-5552 Chemical Structure
 BCP48880 RMC-5552 2382768-62-7
RMC-5552 is a potent and selective inhibitor of mTORC1. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 has anti-cancer activity.
PQR620 Chemical Structure
 BCP25403 PQR620 1927857-56-4
PQR-620 is a novel highly potent and selective mTORC1/2 inhibitor.
Vistusertib sulfate Chemical Structure
 BCP25580 Vistusertib sulfate AZD2014
Vistusertib is a novel mTOR inhibitor with IC50 of 2.8 nM; highly selective against multiple PI3K isoforms (α/β/γ/δ).
MHY-1685 Chemical Structure
 BCP47337 MHY-1685 27406-31-1
MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.
PI3K/mTOR Inhibitor-2 Chemical Structure
 BCP48401 PI3K/mTOR Inhibitor-2 1848242-58-9
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor.
Camonsertib Chemical Structure
 BCP46512 Camonsertib 2417489-10-0
Camonsertib, also known as RP 3500, is aA Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors.
ME-344 Chemical Structure
 BCP46464 ME-344 1374524-68-1
mTOR1/2 Kinase Inhibitor ME-344 is an active metabolite of NV-128, a novel flavonoid small molecule inhibitor of the mammalian Target of Rapamycin (mTOR), with potential antineoplastic activity.
NV-5138 hydrochloride Chemical Structure
 BCP46023 NV-5138 hydrochloride NV5138HCl
NV-5138 (hydrochloride), a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 (hydrochloride) is used for antidepressant studies.
Panulisib Chemical Structure
 BCP44105 Panulisib 1356033-60-7
Panulisib is an orally bioavailable inhibitor of phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR), activin receptor-like kinase 1 (ALK-1) and DNA-dependent protein kinase (DNA-PK), with potential anti-angiogenic and antineoplastic activities.
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