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Chemical Structure Cat. No. Product Name CAS No.
MNK1/2-IN-5 Chemical Structure
BCP46296 MNK1/2-IN-5 1426928-20-2
MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor as a therapeutic agent.
ETC-206 Chemical Structure
BCP30906 ETC-206 1464151-33-4
ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50s of 64 nM and 86 nM, respectively.
eFT508 HCl Chemical Structure
BCP30543 eFT508 HCl 1849590-02-8
eFT508 is a MNK1/2 inhibitor.
EFT-508 Chemical Structure
BCP18993 EFT-508 1849590-01-7
eFT508 is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.
SLV-2436 Chemical Structure
BCP29427 SLV-2436 2095704-43-9
SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8  nM and 5.4 nM, respectively.
CGP 57380 Chemical Structure
BCP27993 CGP 57380 522629-08-9
CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 with IC50 of 2.2 μM, but has no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases.