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Chemical Structure Cat. No. Product Name CAS No.
PI-273 Chemical Structure
BCP46433 PI-273 925069-34-7
PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor. It can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis.
Gilmelisib Chemical Structure
BCP46378 Gilmelisib 1845777-61-8
Gilmelisib is a PI3K inhibitor and antineoplastic.
GSK251 Chemical Structure
BCP46226 GSK251 2125968-05-8
GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode.
NV-5138 hydrochloride Chemical Structure
BCP46023 NV-5138 hydrochloride NV5138HCl
NV-5138 (hydrochloride), a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 (hydrochloride) is used for antidepressant studies.
ETP-45658 Chemical Structure
BCP45165 ETP-45658 1198357-79-7
ETP-45658 is a PI3-kinase inhibitor, also ihibiting DNA-PK and mTOR.
PF-04802367 Chemical Structure
BCP44964 PF-04802367 1962178-27-3
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.
BAY8400 Chemical Structure
BCP44636 BAY8400 BAY8400
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (IC50=81 nM). BAY-8400 can be used for the research of cancer.
IM156 Chemical Structure
BCP44337 IM156 1422365-94-3
IM156, a chemical derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in animal model.
GS-9901 Chemical Structure
BCP44115 GS-9901 1640247-87-5
GS-9901 is a potent, orally active and highly selective inhibitor of PI3Kδ (PI3Kdelta IC50 = 1.0nM, HWB delta EC50 = 1.5 nM; CLpr hHep = 0.05 L/h/kg.).
Panulisib Chemical Structure
BCP44105 Panulisib 1356033-60-7
Panulisib is an orally bioavailable inhibitor of phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR), activin receptor-like kinase 1 (ALK-1) and DNA-dependent protein kinase (DNA-PK), with potential anti-angiogenic and antineoplastic activities.
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