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PI3K/Akt/mTOR

Chemical Structure Cat. No. Product Name CAS No.
RMC-5552 Chemical Structure
 BCP48880 RMC-5552 2382768-62-7
RMC-5552 is a potent and selective inhibitor of mTORC1. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 has anti-cancer activity.
PQR620 Chemical Structure
 BCP25403 PQR620 1927857-56-4
PQR-620 is a novel highly potent and selective mTORC1/2 inhibitor.
Vistusertib sulfate Chemical Structure
 BCP25580 Vistusertib sulfate AZD2014
Vistusertib is a novel mTOR inhibitor with IC50 of 2.8 nM; highly selective against multiple PI3K isoforms (α/β/γ/δ).
MHY-1685 Chemical Structure
 BCP47337 MHY-1685 27406-31-1
MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.
ATM Inhibitor-5 Chemical Structure
 BCP47340 ATM Inhibitor-5 2020089-41-0
M4076 is a higly potent, selective, ATP-competitive inhibitor of ATM kinase with IC50 of 0.2 nM.
Solenopsin Chemical Structure
 BCP48761 Solenopsin 137038-57-4
Solenopsin is an ATP-competitive AKT inhibitor with IC50 value of 10 μM.
SRX3177 Chemical Structure
 BCP48567 SRX3177 2241237-51-2
SRX3177 is a novel potent triple action inhibitor, targeting BRD, PI3K, and CDK.
GSK-3/CDK5/CDK2-IN-1 Chemical Structure
 BCP48519 GSK-3/CDK5/CDK2-IN-1 395074-72-3
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a.
GSK-3 Inhibitor XIII Chemical Structure
 BCP48513 GSK-3 Inhibitor XIII 404828-14-4
GSK-3 Inhibitor XIII is a GSK-3 ATP-binding site inhibitor.
PI3K/mTOR Inhibitor-2 Chemical Structure
 BCP48401 PI3K/mTOR Inhibitor-2 1848242-58-9
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor.
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