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Signaling Pathways
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Neuro Signaling Pathway
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Protease/Metabolic Enzyme
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Research Areas
- Metabolic Disease
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Pyridazine Series
- Ammonia Series
- Amino acid
- Nucleoside Series
- Azaindazole
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrrole Series
- Boric acid
- Pyrimidine Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
MAPK Pathway
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP27823 | Vemurafenib-Analog New | 918505-61-0 |
Vemurafenib-Analog is a potent BRAF inhibitor and the isomer of Vemurafenib.
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BCP24633 | JNK-IN-8 New | 1644498-56-5 |
JNK-IN-8 is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectively.
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BCP24938 | APS-2-79 New | 2002381-25-9 |
APS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling.
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BCP48958 | SR15006 New | 2505001-54-5 |
SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells.
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BCP48906 | ASK1-IN-2 New | 2541792-70-3 |
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM.
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BCP25927 | FR 167653 sulfate New | 158876-66-5 |
FR-167653 is a selective p38 MAPK inhibitor.
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BCP36547 | Selumetinib sulfate New | 943332-08-9 |
Selumetinib Sulfate is the sulfate salt of selumetinib, an orally active, small molecule with potential antineoplastic activity.
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BCP48392 | OTS964 New | 1338542-14-5 |
OTS964 is an orally active, high affinity and selective TOPK inhibitor with an IC50 of 28 nM.
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BCP48492 | GLPG-0259 New | 959754-85-9 |
GLPG-0259 is an inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5).
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BCP48484 | ASN007 benzenesulfonate New | 2055597-39-0 |
ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK. ERK-IN-3 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancers driven by RAS mutations.
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