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ADC Related

Chemical Structure Cat. No. Product Name CAS No.
Bis-PEG1-NHSester Chemical Structure
BCP48565 Bis-PEG1-NHSester 65869-64-9
Bis-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-drug-conjugation (ADC).
PDP-PFP Chemical Structure
BCP47087 PDP-PFP 160580-70-1
PDP-PFP is a reducible ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1).
SMCC Chemical Structure
BCP10445 SMCC 64987-85-5
SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
SG2057 Chemical Structure
BCP46387 SG2057 260417-62-7
SG2057 is a pentyldioxy linked PBD dimer which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts, and also mono-adducts depending on sequence.
SG3199 Chemical Structure
BCP46386 SG3199 1595275-71-0
SG3199 is a PBD dimer which binds in the minor groove of DNA, and forms covalent DNA interstrand cross-links in naked linear plasmid DNA. SG3199 is potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines.
Boc-Val-Ala-PAB-PNP Chemical Structure
BCP46233 Boc-Val-Ala-PAB-PNP 1884578-00-0
Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Mc-Val-Ala-PAB-PNP Chemical Structure
BCP45729 Mc-Val-Ala-PAB-PNP 1639939-40-4
MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
SGD1882 Chemical Structure
BCP45340 SGD1882 1222490-34-7
SGD-1882 is a cytotoxic, DNA minor-groove crosslinking agent pyrrolobenzodiazepine (PBD) dimer, acting as the payload for ADCs.
Mal-PEG4-VA-PBD Chemical Structure
BCP45309 Mal-PEG4-VA-PBD 1342820-68-1
Mal-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA.
BS3 Crosslinker Chemical Structure
BCP45143 BS3 Crosslinker 82436-77-9
BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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