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ADC Related

Chemical Structure Cat. No. Product Name CAS No.
SN-38-D3 Chemical Structure
BCP49629 SN-38-D3 718612-49-8
SN-38-D3 is the deuterium labeled SN-38. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan.
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH Chemical Structure
BCP36301 MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH 1599440-25-1
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
PPC-NB Chemical Structure
BCP49021 PPC-NB 1887040-81-4
PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC).
6-Azido-Hexylamine Chemical Structure
BCP25831 6-Azido-Hexylamine 349553-73-7
6-Azido-Hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
TCO-PEG4-NHS Ester Chemical Structure
BCP43729 TCO-PEG4-NHS Ester 1621096-79-4
TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Bis-PEG1-NHSester Chemical Structure
BCP48565 Bis-PEG1-NHSester 65869-64-9
Bis-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-drug-conjugation (ADC).
PDP-PFP Chemical Structure
BCP47087 PDP-PFP 160580-70-1
PDP-PFP is a reducible ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1).
SMCC Chemical Structure
BCP10445 SMCC 64987-85-5
SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
SG2057 Chemical Structure
BCP46387 SG2057 260417-62-7
SG2057 is a pentyldioxy linked PBD dimer which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts, and also mono-adducts depending on sequence.
SG3199 Chemical Structure
BCP46386 SG3199 1595275-71-0
SG3199 is a PBD dimer which binds in the minor groove of DNA, and forms covalent DNA interstrand cross-links in naked linear plasmid DNA. SG3199 is potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines.
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