Home   >  
Epigenetics
  >  
Epigenetic Reader Domain

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Epigenetic Reader Domain

Chemical Structure Cat. No. Product Name CAS No.
PFI-4 Chemical Structure
 BCP23818 PFI-4 900305-37-5
PFI-4 is a potent and highly selective BRPF1 Bromodomain (BRPF1B) inhibitor, with an IC50 of 172 nM. PFI-4 can be used to explore the functional mechanisms of the HBO1/BRPF1 complex and to study bone loss and osteolytic malignant bone lesions.
BAZ2-ICR Chemical Structure
 BCP23999 BAZ2-ICR 1665195-94-7
BAZ2-ICR is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. BAZ2-ICR is an epigenetic chemical probe.
BMS 986158 Chemical Structure
 BCP25147 BMS 986158 1800340-40-2
BMS-986158 is an inhibitor of the bromodomain and extra-terminal (BET) proteins.
SRX3177 Chemical Structure
 BCP48567 SRX3177 2241237-51-2
SRX3177 is a novel potent triple action inhibitor, targeting BRD, PI3K, and CDK.
AU-15330 Chemical Structure
 BCP46987 AU-15330 2380274-50-8
AU-15330 is a novel, highly specific and VHL-dependent PROTAC degrader of SWI/SNF ATPase components (SMARCA2, SMARCA4 and PBRM1) that shows preferential cytotoxicity in enhancer-binding transcription factor-addicted cancers at low nanomolar concentrations.
EML 425 Chemical Structure
 BCP46797 EML 425 1675821-32-5
EML425 is a potent and selective CREB binding protein (CBP)/p300 inhibitor with IC50s of 2.9 and 1.1 μM, respectively.
CFT-8634 Chemical Structure
 BCP46564 CFT-8634 2704617-96-7
CFT-8634 is a degrader targeting BRD9 extracted from patent WO2021178920A1 compound 173.
GSK1379725A Chemical Structure
 BCP46513 GSK1379725A 1802251-00-8
GSK1379725A is the first selective inhibitor of BPTF over Brd4.
BAZ1A-IN-1 Chemical Structure
 BCP46449 BAZ1A-IN-1 941521-45-5
BAZ1A-IN-1 is a potent inhibitor of BAZ1A (bromodomain-containing protein). BAZ1A-IN-1 shows a KD value of 0.52 μM against BAZ1A bromodomain.
M-525 Chemical Structure
 BCP46311 M-525 2173582-08-4
M-525 is a first-in-class, highly potent, irreversible small-molecule inhibitor of the menin-MLL interaction.
123下一页末页共 139 条记录 1 / 14 页 
0086-13720134139