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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
DC_AC50 Chemical Structure
 BCP49129 DC_AC50 497061-48-0
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.
BCL6-IN-3 Chemical Structure
 BCP49128 BCL6-IN-3 2253878-44-1
BCL6-IN-3 is a potent BCL6 degrader.
Pyridoclax Chemical Structure
 BCP23863 Pyridoclax 1651890-44-6
Pyridoclax is a potential Mcl-1 inhibitor.
AVN-944 Chemical Structure
 BCP23877 AVN-944 297730-17-7
AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism, DNA replication, apoptosis and cell cycle control. AVN944 has been associated with cancer cell death in clinical trials. It is being investigated for the treatment of patients with advanced hematologic malignancies.
Buthionine sulfoximine Chemical Structure
 BCP24029 Buthionine sulfoximine 5072-26-4
DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
MGH-CP1 Chemical Structure
 BCP49045 MGH-CP1 896657-58-2
MGH-CP1 is a potent and selective TEAD palmitoylation inhibitor.
UTL-5g Chemical Structure
 BCP48944 UTL-5g 646530-37-2
UTL-5g (GBL-5g), an anti-inflammatory TNF-α inhibitor, has chemoprotective and liver radioprotective effects. UTL-5g lowers hepatotoxicity, nephrotoxicity, and myelotoxicity induced by Cisplatin through TNF-α inhibition among other factors.
SW106065 Chemical Structure
 BCP48935 SW106065 62289-81-0
SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). SW106065 inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 µM. SW106065 can be used for MPNST research.
Pifithrin-alpha, p-Nitro, Cyclic Chemical Structure
 BCP25188 Pifithrin-alpha, p-Nitro, Cyclic 60477-38-5
Pifithrin-α, p-Nitro, Cyclic is cell-permeable and active-form p53 inhibitor.
PD-1/PD-L1 Inhibitor 4 Chemical Structure
 BCP25721 PD-1/PD-L1 Inhibitor 4 1629655-94-2
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