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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
Brigimadlin Chemical Structure
BCP49630 Brigimadlin 2095116-40-6
Brigimadlin (BI 907828) is an E3 ubiquitin-protein ligase MDM-2 inhibitor. Brigimadlin serves as an antineoplastic agent.
PC-14586 Chemical Structure
BCP49506 PC-14586 PC-14586
PC14586 targets p53 Y220C mutants to selectively reactivate p53.
SAR-443820 Chemical Structure
BCP49450 SAR-443820 SAR-443820
SAR443820 is a central nervous system (CNS)-penetrant small molecule inhibitor of RIPK1.
 Chemical Structure
ABD328 Chemical Structure
BCP49194 ABD328 1055896-19-9
ABD328 is an orally active, small molecule inhibitor of RANKL and TNF signalling that inhibits inflammation in vivo.
DC_AC50 Chemical Structure
BCP49129 DC_AC50 497061-48-0
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.
BCL6-IN-3 Chemical Structure
BCP49128 BCL6-IN-3 2253878-44-1
BCL6-IN-3 is a potent BCL6 degrader.
Pyridoclax Chemical Structure
BCP23863 Pyridoclax 1651890-44-6
Pyridoclax is a potential Mcl-1 inhibitor.
AVN-944 Chemical Structure
BCP23877 AVN-944 297730-17-7
AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism, DNA replication, apoptosis and cell cycle control. AVN944 has been associated with cancer cell death in clinical trials. It is being investigated for the treatment of patients with advanced hematologic malignancies.
Buthionine sulfoximine Chemical Structure
BCP24029 Buthionine sulfoximine 5072-26-4
DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
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