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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
M351-056 Chemical Structure
 BCP44929 M351-056 M351-056
M351-056 is a novel VISTA (V-domain immunoglobulin suppressor of T-cell activation) agonist.
M351-110 Chemical Structure
 BCP44928 M351-110 M351-110
M351-110 is a novel VISTA (V-domain immunoglobulin suppressor of T-cell activation) agonist.
ZZW-115 3HCl Chemical Structure
 BCP44912 ZZW-115 3HCl 10122-45-9
ZZW-115 hydrochloride is a potent NUPR1 inhibitor, with a Kd of 2.1 μM.
NAE-IN-M22 Chemical Structure
 BCP44660 NAE-IN-M22 864420-54-2
NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.
Necrostatin-34 Chemical Structure
 BCP44627 Necrostatin-34 375835-43-1
Necrostatin-34, a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
AN0128 Chemical Structure
 BCP44562 AN0128 872044-70-7
AN0128 is a tumour necrosis factor alpha (TNF-α) inhibitor potentially for the treatment of atopic dermatitis.
ADPM06 Chemical Structure
 BCP44534 ADPM06 490035-90-0
ADPM06 is an emerging non-porphyrin PDT agent which has been specifically designed for therapeutic application.
RIPA-56 Chemical Structure
 BCP44340 RIPA-56 1956370-21-0
RIPA-56 is a highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1) with an IC50 of 13 nM.
CLEFMA Chemical Structure
 BCP44188 CLEFMA 1246964-32-8
CLEFMA Activates the Extrinsic and Intrinsic Apoptotic Processes through JNK1/2 and p38 Pathways in Human Osteosarcoma Cells
Euphorbia Factor L2 Chemical Structure
 BCP44168 Euphorbia Factor L2 218916-51-9
Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer.
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