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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
Pifithrin-alpha, p-Nitro, Cyclic Chemical Structure
 BCP25188 Pifithrin-alpha, p-Nitro, Cyclic 60477-38-5
Pifithrin-α, p-Nitro, Cyclic is cell-permeable and active-form p53 inhibitor.
PD-1/PD-L1 Inhibitor 4 Chemical Structure
 BCP25721 PD-1/PD-L1 Inhibitor 4 1629655-94-2
2'-Fucosyllactose Chemical Structure
 BCP47768 2'-Fucosyllactose 41263-94-9
2'-Fucosyllactose is an oligosaccharide that could be derived from human milk.
NSC 146109 hydrochloride Chemical Structure
 BCP48536 NSC 146109 hydrochloride 59474-01-0
NSC 146109 hydrochloride is a small-molecule p53 activator that target MDMX and can be used for breast cancer research. NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes.
(R)-MIK665 Chemical Structure
 BCP47788 (R)-MIK665 1799831-02-9
(R)-MIK665 is the less active enantiomer of MIK665. MIK665 is a special Mcl-1 inhibitor with an IC50 of 1.81 nM.
Eclitasertib Chemical Structure
 BCP48186 Eclitasertib 2125450-76-0
Eclitasertib is a receptor-interacting serine/ threonine protein (RIP-1) kinase inhibitor.
Z-VAD(OH)-FMK Chemical Structure
 BCP47286 Z-VAD(OH)-FMK 161401-82-7
Z-VAD(OH)-FMK is an irreversible pan-caspase inhibitor.
Lisaftoclax Chemical Structure
 BCP47569 Lisaftoclax 2180923-05-9
Lisaftoclax exhibits IC50 values of 5.5 nM and 6.4 nM in Bcl-2 dependent RS4;11 cells and Bcl-xl dependent Molm13 cells.
ONC-201 Dihydrochloride Chemical Structure
 BCP46830 ONC-201 Dihydrochloride 1638178-82-1
ONC-201, also known as TIC10, is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.
NiCur Chemical Structure
 BCP46796 NiCur 63476-70-0
NiCur is an inhibitor of p53 with an IC50 value of 0.35 μM.
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