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GPCR/G Protein
Prostaglandin Receptor

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Prostaglandin Receptor

Chemical Structure Cat. No. Product Name CAS No.
Tranilast sodium Chemical Structure
BCP46779 Tranilast sodium 104931-56-8
Tranilast sodium acts as an anti-atopic agent.
Crisdesalazine Chemical Structure
BCP44811 Crisdesalazine 927685-43-6
Crisdesalazine, also known as AAD-2004, is a microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor potentially for the treatment of Alzheimer's type dementia, Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Arthritis, Depression, Diabetes and Pancreatitis.
Prostaglandin G2 Chemical Structure
BCP42810 Prostaglandin G2 51982-36-6
Prostaglandin G2 is a prostaglandins G.
Pizuglanstat Chemical Structure
BCP42640 Pizuglanstat 1244967-98-3
Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor.
BAY 1316957 Chemical Structure
BCP40674 BAY 1316957 1613264-40-6
BAY-1316957 is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist (IC50= 15.3 nM ) with excellent drug metabolism and pharmacokinetics properties.
U-46619 Chemical Structure
BCP39866 U-46619 56985-40-1
U46619 is a PGH2 (TXA2) analog that is a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM).
BGC-20-1531 Chemical Structure
BCP37893 BGC-20-1531 1186532-61-5
BGC-20-1531 is a EP4 antagonist for the treatment of acute migraine.
ONO-8130 Chemical Structure
BCP37875 ONO-8130 459841-96-4
ONO-8130 is an orally available EP1 receptor antagonist.
DG-041 Chemical Structure
BCP35669 DG-041 861238-35-9
DG 041 inhibits PGE2 facilitation of platelet aggregation in vitro and ex vivo. Displays good plasma and metabolic stability.
TG4-155 Chemical Structure
BCP25837 TG4-155 1164462-05-8
TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. It blocks the induced expression of inflammatory markers in microglial cells.
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