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Protease/Metabolic Enzyme
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Cytochrome P450

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Cytochrome P450

Chemical Structure Cat. No. Product Name CAS No.
Anastrozole Chemical Structure
BCP02090 Anastrozole 120511-73-1
Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor.
Cytochrome P450 14a-demethylase inhibitor 1J Chemical Structure
BCP23782 Cytochrome P450 14a-demethylase inhibitor 1J 1155361-08-2
Cytochrome P450 14a-demethylase inhibitor 1J is an inhibitor of CYP isoenzymes and an antifungal agent.
Mefentrifluconazole Chemical Structure
BCP48583 Mefentrifluconazole 1417782-03-6
Mefentrifluconazole, a new azole derivative, is a broad-spectrum antifungal agent. Mefentrifluconazole is a highly selective and orally active fungal CYP51 inhibitor (Kd= 0.5 nM).
K-11777 Chemical Structure
BCP48070 K-11777 233277-99-1
K-11777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively.
8,9-Eet Chemical Structure
BCP47805 8,9-Eet 81246-85-7
(±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid. (±)8(9)-EET is a major cytochrome P450 (CYP450) metabolite in the renal cortex.
11,12-Eet Chemical Structure
BCP47804 11,12-Eet 81276-02-0
(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. ​
CAY10462 Chemical Structure
BCP48084 CAY10462 502656-68-0
CAY10462 is the hydrochloride salt of CAY10434 and selective inhibitor of the 20-HETE synthase CYP4A11 exhibiting an IC50 of 8.8 nM when tested in human renal microsomes.
CAY10434 Chemical Structure
BCP48083 CAY10434 769917-29-5
CAY10434 is a selective inhibitor of the 20-HETE synthase CYP4A11.
Oteseconazole Chemical Structure
BCP47038 Oteseconazole 1340593-59-0
Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51.
DMU2139 Chemical Structure
BCP46829 DMU2139 1821143-80-9
DMU2139 is a potent and specific CYP1B1 inhibitor, with IC50s of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively.
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