Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Neurotensin Receptor
- Melatonin Receptor
- Urotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Cholecystokinin Receptor
- Somatostatin Receptor
- Adenylate Cyclase
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- Adenosine Receptor
- OX Receptor
- Prostaglandin Receptor
- Glucagon Receptor
- NK Receptor
- GnRH Receptor
- Leukotriene Receptor
- Glucocorticoid Receptor
- mAChR
- P2 Receptor
- GPR
- CGRP Receptor
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Opioid Receptor
- Vasopressin Receptor
- Smoothened/Smo
- mGluR
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Monoamine Oxidase
- Imidazoline Receptor
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- mGluR
- Histamine Receptor
- Adrenergic Receptor
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- nAChR
- CGRP Receptor
- FAAH
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- Xanthine Oxidase
- Mitochondrial Metabolism
- ACC
- Pyruvate Kinase
- ALDH
- SCD
- Serine Protease
- CETP
- Neprilysin
- MAGL
- MLR
- FTase
- Carbonic Anhydrase
- Elastase
- E1 E2 E3 Enzyme
- PAI1
- ROR
- NOX
- Glucokinase
- Aldose Reductase
- FAS
- Tyrosinase
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HSP
- HCV Protease
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phospholipase
- Phosphodiesterase/PDE
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Diabetes
- Endocrinology
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Pyridazine Series
- Azaindazole
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrimidine Series
- Boric acid
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Indazole Series
- Piperidine Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
CXCR
Chemical Structure | Cat. No. | Product Name | CAS No. |
---|
|
![]() |
BCP45761 | ML339 New | 2579689-83-9 |
ML-339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM).
|
![]() |
BCP45167 | ML 145 New | 1164500-72-4 |
ML 145 is a selective antagonist for the GPR35 orphan receptor GPCR (IC50 = 20.1 nM). Over 1000-fold more selective for GPR35 compared to GPR55 antagonists.
|
![]() |
BCP37842 | VUF11418 New | 1414376-85-4 |
VUF11418 first reported nonpeptidomimetic agonist on The G protein-coupled chemokine receptor CXCR3.
|
![]() |
BCP34887 | VUF11207 fumarate New | 1785665-61-3 |
VUF11207 fumarate is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7.
|
![]() |
BCP34188 | ALX 40-4C New | 143413-49-4 |
ALX 40-4C is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.
|
![]() |
BCP34091 | NBI-74330 New | 855527-92-3 |
NBI-74330 is a small molecule antagonist for CXCR3
|
![]() |
BCP33234 | USL311 New | 1373268-67-7 |
USL311 is a selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4.
|
![]() |
BCP26048 | Mavorixafor trihydrochloride New | 880549-30-4 |
Mavorixafor is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.
|
![]() |
BCP32594 | BX471 hydrochloride New | 288262-96-4 |
BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
|
