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GPCR/G Protein

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Chemical Structure Cat. No. Product Name CAS No.
MLS000532223 Chemical Structure
BCP48911 MLS000532223 16616-39-0
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases. It prevents GTP binding to several GTPases. Small GTPases are key regulators of cellular activity .
AMG 510 Racemate Chemical Structure
BCP30799 AMG 510 Racemate AMG510Racemate
RM-018 Chemical Structure
BCP48790 RM-018 2641993-55-5
RM-018 is an inhibitor of the active state of KRASG12C. Rm-018 retains the ability to bind and inhibit KRASG12C/Y96D. Rm-018 combines with GTP-bound to activate the [" RAS(ON) "] state of KRASG12C.
ASP2453 Chemical Structure
BCP48490 ASP2453 2241719-73-1
ASP2453 is a potent, selective and covalent KRAS G12C inhibitor.
AZA1 Chemical Structure
BCP48765 AZA1 1071098-42-4
AZA1 is a potent dual inhibitor of Rac1 and Cdc42.
KRAS G12C inhibitor 54 Chemical Structure
BCP48764 KRAS G12C inhibitor 54 2765580-17-2
KRAS G12C inhibitor 54 is a KRAS G12C inhibitor.
GDC-6036-NH Chemical Structure
BCP48491 GDC-6036-NH 2417918-80-8
GDC-6036-NH is from patent WO2020097537A2, and a precursor of compound 17 a/b. Compound 17 a/b is a RAS inhibitor and can be used in cancer research.
RMC-0331 Chemical Structure
BCP48495 RMC-0331 2488788-52-7
RMC-0331 is a potent, selective and orally bioavailable SOS1 inhibitor.
ZINC69391 Chemical Structure
BCP47279 ZINC69391 303094-67-9
ZINC69391 is a specific Rac1 inhibitor. It acts by interferring with the interaction of Rac1 with Dock180, a relevant Rac1 activator in glioma invasion, and by reducing Rac1-GTP levels.
6H05 trifluoroacetate Chemical Structure
BCP46758 6H05 trifluoroacetate 2061344-88-3
6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).
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