Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Neurotensin Receptor
- Melatonin Receptor
- Urotensin Receptor
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Neuro Signaling Pathway
- Monoamine Oxidase
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- NK Receptor
- Beta secretase
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- P glycoprotein
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- nAChR
- CGRP Receptor
- FAAH
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- NFκB
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-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
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- ACC
- Pyruvate Kinase
- ALDH
- SCD
- Serine Protease
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- E1 E2 E3 Enzyme
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- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phospholipase
- Phosphodiesterase/PDE
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Pyridazine Series
- Azaindazole
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrimidine Series
- Boric acid
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Indazole Series
- Piperidine Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
JNK
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP43705 | Indirubin-3'-oxime New | 667463-82-3 |
Indirubin-3'-monoxime, a synthetic derivative of indirubin, is a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Indirubin-3′-oxime directly inhibits the activity of all three isoforms of JNK (JNK1, JNK2, and JNK3), with IC50s of 0.8 μM, 1.4 μM, and 1.0 μM, respectively. Indirubin-3′-oxime can enhance height growth via activation of Wnt/β-catenin signaling in chondrocytes.
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BCP38621 | CC-90001 New | 1403859-14-2 |
CC-90001 is a potent and selective JNK inhibitor, which is 12.9-fold more potent for JNK1 inhibition than JNK2 in a cell-based model.
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BCP35736 | Urolithin B New | 1139-83-9 |
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
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BCP34038 | DTP3 TFA New | DTP3 |
DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.
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BCP32871 | AS601245 New | 345987-15-7 |
AS601245 is a cell-permeable JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
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BCP32078 | SU 3327 New | 40045-50-9 |
SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM) with selectivity over p38 MAPK and Akt. SU 3327 inhibits the interaction between JNK and JIP (IC50 = 239 nM).
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BCP17485 | IQ-1S | 23146-22-7 |
IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
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BCP25004 | CC-401 hydrochloride | 1438391-30-0 |
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.
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BCP16456 | DB-07268 | 929007-72-7 |
DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.
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BCP01960 | CC-401 | 395104-30-0 |
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
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