Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Somatostatin Receptor
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- PAR
- Neuropeptide Receptor
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- Prostaglandin Receptor
- OX Receptor
- Adenosine Receptor
- Glucagon Receptor
- NK Receptor
- GnRH Receptor
- Leukotriene Receptor
- Glucocorticoid Receptor
- mAChR
- P2 Receptor
- GPR
- CGRP Receptor
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Smoothened/Smo
- Vasopressin Receptor
- Opioid Receptor
- mGluR
- Cannabinoid Receptor
- Dopamine Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- nAChR
- FAAH
- CGRP Receptor
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- Xanthine Oxidase
- Carboxypeptidase
- 11β HSD
- ACC
- Mitochondrial Metabolism
- Pyruvate Kinase
- ALDH
- Serine Protease
- SCD
- Neprilysin
- FTase
- CETP
- MLR
- Carbonic Anhydrase
- MAGL
- E1 E2 E3 Enzyme
- PAI1
- Elastase
- NOX
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HSP
- HCV Protease
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phospholipase
- Phosphodiesterase/PDE
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Infection
- Inflammation
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Pyridazine Series
- Ammonia Series
- Amino acid
- Nucleoside Series
- Azaindazole
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrrole Series
- Boric acid
- Pyrimidine Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
FGFR
Chemical Structure | Cat. No. | Product Name | CAS No. |
---|
![]() |
BCP46381 | MAX-40279 hemifumarate New | 2388506-43-0 |
MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase.
|
![]() |
BCP46362 | FGFR2-IN-2 New | 2677709-81-6 |
FGFR2-IN-2 is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively.
|
![]() |
BCP46003 | MAX-40279 hemiadipate New | 2388506-44-1 |
MAX-40279 hemiadipate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase.
|
![]() |
BCP46002 | MAX-40279 New | 2070931-57-4 |
MAX-40279 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) and FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2), with potential antineoplastic activity.
|
![]() |
BCP44116 | SU4984 New | 186610-89-9 |
SU4984 is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1 (FGFR1; IC50 = 10-20 µM).
|
![]() |
BCP43801 | PF-05231023 New | 1037589-69-7 |
PF-05231023 is a long-acting FGF21 mimetic. PF-05231023 decreases body weight and improves lipid profile in non-human primates and in type 2 diabetic subjects.
|
![]() |
BCP43695 | Heparitin, sulfate New | 9050-30-0 |
Heparan sulfate, a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix.
|
![]() |
BCP37851 | PD089828 New | 179343-17-0 |
PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC50s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC50=0.18 µM). PD-089828 also inhibits MAPK with an IC50 of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity.
|
![]() |
BCP31812 | Pemigatinib New | 1513857-77-6 |
Pemigatinib is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.
|
![]() |
BCP25142 | Rogaratinib New | 1443530-05-9 |
Rogaratinib is a potent and selective fibroblast growth factor receptor (FGFR) inhibitor.
|
