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Apoptosis Pathway
TNF Receptor

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TNF Receptor

Chemical Structure Cat. No. Product Name CAS No.
AN0128 Chemical Structure
BCP44562 AN0128 872044-70-7
AN0128 is a tumour necrosis factor alpha (TNF-α) inhibitor potentially for the treatment of atopic dermatitis.
UCB-9260 Chemical Structure
BCP40717 UCB-9260 1515888-53-5
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer.
(Rac)-Benpyrine Chemical Structure
BCP37768 (Rac)-Benpyrine 1333714-43-4
(Rac)-Benpyrine is a racemate of Benpyrine. (Rac)-Benpyrine is a potent and orally active TNF-α inhibitor and has the potential for TNF-α mediated inflammatory and autoimmune disease research.
Corilagin Chemical Structure
BCP25487 Corilagin 23094-69-1
Corilagin, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. It is an inhibitor of TNF-α.
Hispidol Chemical Structure
BCP32790 Hispidol 5786-54-9
Hispidol is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 µM.
Methylthiouracil Chemical Structure
BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
Shikonin Chemical Structure
BCP29329 Shikonin 517-89-5
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin has shown various biological activities, including inhibition of TNF-α, NF-κB, HIV-1.
C25-140 Chemical Structure
BCP30323 C25-140 1358099-18-9
C25-140 is the first in class protein-protein interaction inhibitor of a RING-E3 ligase (TRAF6) / E2 enzyme (Ubc13) binding.
Golimumab Chemical Structure
BCP30499 Golimumab 476181-74-5
Golimumab (CNTO 148) is a human monoclonal antibody which is used as an immunosuppressive drug. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor.
Etanercept Chemical Structure
BCP12862 Etanercept 185243-69-0
Etanercept is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.
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