Home   >  
Apoptosis Pathway
  >  
p53

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

p53

Chemical Structure Cat. No. Product Name CAS No.
NiCur Chemical Structure
BCP46796 NiCur 63476-70-0
NiCur is an inhibitor of p53 with an IC50 value of 0.35 μM.
CP-31398 dihydrochloride Chemical Structure
BCP43517 CP-31398 dihydrochloride 1217195-61-3
CP-31398 dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53.
PK11007 Chemical Structure
BCP32609 PK11007 874146-69-7
PK11007 is a mild thiol alkylator with anticancer activity. PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels.
(−)-Nutlin-3 Chemical Structure
BCP29278 (−)-Nutlin-3 548472-68-0
Nutlin 3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM.
PK11007 Chemical Structure
BCP30143 PK11007 38275-34-2
PK11007 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
Pifithrin-β hydrobromide Chemical Structure
BCP17578 Pifithrin-β hydrobromide 511296-88-1
Pifithrin-β is a potent p53 inhibitor with an IC50 of 23 μM.
CP 31398 Chemical Structure
BCP14611 CP 31398 259199-65-0
CP 31398 dihydrochloride is a potent activator of p53 with maximum tolerated dose of 400 ppm.
CBL0137 Chemical Structure
BCP29977 CBL0137 1197996-80-7
CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 of 0.47 μM.
Prima-1 Chemical Structure
BCP26191 Prima-1 5608-24-2
Prima-1 is an inhibitor of the growth of cell lines derived from various human tumor types in a mutant p53-dependent manner.
COTI-2 Chemical Structure
BCP28961 COTI-2 1039455-84-9
COTI-2 is a small molecule candidate anti-cancer drug which can convert mutant p53 to wild-type conformation.
123下一页末页共 40 条记录 1 / 4 页 
0086-13720134139