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Ion Channel/Membrane Transporter

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Chemical Structure Cat. No. Product Name CAS No.
Opiranserin Chemical Structure
BCP48961 Opiranserin 1441000-45-8
Opiranserin is a glycine transporter inhibitor and serotonin receptor antagonist. Opiranserin is a drug candidate.
Sarcosine Chemical Structure
BCP34413 Sarcosine 107-97-1
Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.
Org 25543 hydrochloride Chemical Structure
BCP33172 Org 25543 hydrochloride 495076-64-7
Org 25543 hydrochloride is a potent and selective GlyT2 inhibitor (IC50 = 16 nM for hGlyT2).
LY2365109 hydrochloride Chemical Structure
BCP32606 LY2365109 hydrochloride 1779796-27-8
LY2365109 HCl is a potent and selective glycine transporter 1 (GlyT1) inhibitor.
PF-03463275 HCl Chemical Structure
BCP32015 PF-03463275 HCl 1173177-11-1
PF-03463275 is an orally available, CNS-penetrant inhibitor of SLC6A9, the GlyT1 glycine transporter, developed for potential anti-schizophrenia activity.
Org 25935 hydrochloride Chemical Structure
BCP27717 Org 25935 hydrochloride 949588-40-3
Org-25935, also called SCH-900435, is a GlyT-1 inhibitor potentially for the treatment of schizophrenia and alcohol dependence.
NFPS Chemical Structure
BCP17140 NFPS 405225-21-0
NFPS is a selective non-transportable GlyT1 inhibitor
ALX 5407 Chemical Structure
BCP21210 ALX 5407 571147-18-7
ALX 5407 is a potent, selective GlyT1 inhibitor that demonstrates >10-fold greater activity in in vitro functional glycine reuptake assay than racemic (±)-NFPS.
GlyT2-IN-1 Chemical Structure
BCP29380 GlyT2-IN-1 448947-81-7
GlyT2-IN-1 is a glycine transporters GLYT2 inhibitor.
Bitopertin Chemical Structure
BCP05690 Bitopertin 845614-11-1
RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).