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Wnt/Stem Cell

Chemical Structure Cat. No. Product Name CAS No.
BUN34616 Chemical Structure
 BCP46436 BUN34616 2111834-61-6
BUN34616 is a potent and selective inhibitor of phosphorylation and transcriptional activity of STAT5.
SC-1 Chemical Structure
 BCP46435 SC-1 1313019-65-6
SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.
AZD4205 Chemical Structure
 BCP46221 AZD4205 2091134-35-7
AZD4205 is a highly potent JAK1-selective kinase inhibitor with excellent preclinical pharmacokinetics with potential for further clinical development. JAK1 is part of the JAK1/signal transducer and activator of transcription (STAT) axis, which plays an important role in tumour escape from EGFR-targeted treatment.
Ifidancitinib Chemical Structure
 BCP46085 Ifidancitinib 1236667-40-5
Ifidancitinib is a Janus kinase inhibitor.
Ritlecitinib tosylate Chemical Structure
 BCP45991 Ritlecitinib tosylate 2192215-81-7
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor.
Deuruxolitinib phosphate Chemical Structure
 BCP45990 Deuruxolitinib phosphate 2147706-60-1
Deuruxolitinib(CTP-543), an oral inhibitor of Janus kinases JAK1 and JAK2, as a potential treatment for alopecia areata.
JAK-IN-5 Chemical Structure
 BCP45656 JAK-IN-5 2096999-92-5
JAK-IN-5 is an inhibitor of JAK.
Tyk2-IN-5 Chemical Structure
 BCP45577 Tyk2-IN-5 1797432-62-2
Tyk2-IN-5 is a highly potent, selective and orally active Tyk2 inhibitor and targets the JH2 domain, with a Ki of 0.086 nM for Tyk2 JH2 and an IC50 of 25 nM for IFNα.
VT-103 Chemical Structure
 BCP45566 VT-103 2290608-13-6
VT103, an analog of VT101, is an orally active and selective TEAD1 protein palmitoylation inhibitor.
HLY78 Chemical Structure
 BCP45530 HLY78 854847-61-3
HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction.
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