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Wnt/Stem Cell

Chemical Structure Cat. No. Product Name CAS No.
Super-TDU Chemical Structure
 BCP25144 Super-TDU 1599441-71-0
Super-TDU is an inhibitory peptide targeting YAP-TEADs interaction.
H-1152 Dihydrochloride Chemical Structure
 BCP25257 H-1152 Dihydrochloride 871543-07-6
H-1152 dihydrochloride is an isoquinolinesulfonamide derivative that is a membrane-permeable inhibitor of Rho-kinase but poor inhibitor of other serine/threonine kinases.
Ruxolitinib racemic Chemical Structure
 BCP25428 Ruxolitinib racemic 1160597-27-2
Ruxolitinib racemic is a Janus-associated kinase (JAK) inhibitor.
inS3-54-A18 Chemical Structure
 BCP48402 inS3-54-A18 328998-53-4
inS3-54A18 is a potent STAT3 inhibitor, with anti-cancer properties.
GSK-3/CDK5/CDK2-IN-1 Chemical Structure
 BCP48519 GSK-3/CDK5/CDK2-IN-1 395074-72-3
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a.
β-catenin-IN-2 Chemical Structure
 BCP48537 β-catenin-IN-2 1458664-10-2
β-catenin-IN-2 is a potent β-catenin inhibitor, compound H1B1, extracted from patent US20150374662A1.
TED-347 Chemical Structure
 BCP48533 TED-347 2378626-29-8
TED-347 is a covalent inhibitor of TEAD4-Yap1 protein-protein interaction in mammalian cells which blocks iTEAD transcriptional activity and inhibits glioblastoma cell viability.
TDI-011536 Chemical Structure
 BCP45820 TDI-011536 2687970-96-1
TDI-011536 is a potent, ATP-competitive inhibitor of Lats kinases with IC50 of 0.76 nM (2 mM ATP) in vitro assays, prevents Yap phosphorylation in the cell-based assays with EC50 of 10 nM.
WAY316606 Chemical Structure
 BCP48249 WAY316606 915759-45-4
WAY-316606, a specific antagonist of SFRP1, functions as an activator of canonical Wnt/β-catenin signalling in the human hair bulb.
GDC-0214 Chemical Structure
 BCP47996 GDC-0214 1831144-46-7
GDC0214 is a potent, selective inhalable and lung-restricted inhibitor of JAK1 with IC50 of 8.52 nM, displays 6.3/704/28 fold selectivity over JAK2/JAK3/TYK2.
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