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Ion Channel/Membrane Transporter
Proton Pump

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Proton Pump

Chemical Structure Cat. No. Product Name CAS No.
Rohitukine Chemical Structure
BCP44052 Rohitukine 71294-60-5
Rohitukine is an anti-cancer agent. It acts through gastrin antagonism and H(+) K (+)-ATPase inhibition to modulate apoptosis pathways. Rohitukine ia an antidyslipidemic, antiadipogenic, gastroprotective, antifertility, and antileishmanial compound.
Pumaprazole Chemical Structure
BCP43168 Pumaprazole 158364-59-1
Pumaprazole is a potent, selective and reversible proton pump antagonist. Both before and after cure of H. pylori infection, pumaprazole raised the intragastric pH over a 24-h period to a similar degree as omeprazole. H. pylori infection similarly augments the pH-increasing effect of both drugs. This effect is related to H. pylori infection and not to an increased activation of acid inhibitory agents in the parietal cell compartment.
Tegoprazan Chemical Structure
BCP38351 Tegoprazan 942195-55-3
Tegoprazan is a potassium-competitive acid blocker that controls gastric acid secretion and motility.
EN6 Chemical Structure
BCP34911 EN6 1808714-73-9
EN6 is a novel covalent autophagy activator targeting cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase which activates mTORC1 via the Rag guanosine triphosphatases.
(r)-Omeprazole Chemical Structure
BCP21299 (r)-Omeprazole 119141-89-8
(R)-omeprazole is a 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has R configuration at the sulfur atom. It is an enantiomer of an esomeprazole.
(R)-(+)-Pantoprazole magnesium salt Chemical Structure
BCP20280 (R)-(+)-Pantoprazole magnesium salt 657391-79-2
Pantoprazole is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
Concanamycin A Chemical Structure
BCP21840 Concanamycin A 80890-47-7
Concanamycin A is a specific inhibitor of V-type (vacuolar) H+-ATPase that displays > 2000-fold selectivity over other H+-ATPases (IC50 values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H+-ATPases and porcine P-type Na+,K+-ATPase respectively).
Ufiprazole Chemical Structure
BCP21782 Ufiprazole 73590-85-9
Omeprazole sulfide is a metabolite of Omeprazole, which is a proton pump inhibitor.
Bedakillin Chemical Structure
BCP21751 Bedakillin 654653-81-3
Bedakillin acts on the proton pump of the ATP-synthase enzyme , which is a different mechanism of action than for quinolones targeting DNA-gyrase .
Vonoprazan Fumarate Chemical Structure
BCP13238 Vonoprazan Fumarate 881681-01-2
Vonoprazan is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.
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