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5 HT Receptor/Serotonin Receptor

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5 HT Receptor/Serotonin Receptor

Chemical Structure Cat. No. Product Name CAS No.
(S)-Amisulpride Chemical Structure
BCP44351 (S)-Amisulpride 71675-92-8
(S)-Amisulpride is a potent D2 and D3 receptor antagonist, also acting as a potent antagonist at the 5-HT7 receptor.
Amisulpride hydrochloride Chemical Structure
BCP44352 Amisulpride hydrochloride 81342-13-4
Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.
Pimethixene Chemical Structure
BCP43719 Pimethixene 314-03-4
Pimethixene is antihistamine and anticholinergic of the thioxanthene chemical class that is often used to treat hyperactivity, anxiety, sleep disorders, and allergy. It is also used for anesthesia and as a bronchodilator (to dilate the bronchi and bronchioles for more airflow).
Pimethixene maleate Chemical Structure
BCP43718 Pimethixene maleate 13187-06-9
Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively.
SB 203186 hydrochloride Chemical Structure
BCP42428 SB 203186 hydrochloride 135938-17-9
SB203186 is potent 5-HT4 receptor antagonist with high affinity for human atrial 5-HT4 receptors.
Indophagolin Chemical Structure
BCP41936 Indophagolin 1207660-00-1
Indophagolin is a potent autophagy inhibitor with and IC50 value of 140 nM. Indophagolin also shows activity on the purinergic receptors with IC50 values of 2.40 μM, 3.49 μM and 2.71 μM for the P2X1, P2X3 and P2X4 receptors, respectively.
Buspirone Chemical Structure
BCP41132 Buspirone 36505-84-7
Buspirone is an anxiolytic psychotropic drug of the azapirone chemical class. It is primarily used to treat generalized anxiety disorder (GAD). Unlike most drugs predominantly used to treat anxiety, buspirone's pharmacology is not related to benzodiazepines or barbiturates, and so does not carry the risk of physical dependence and withdrawal symptoms for which those drug classes are known.
RS67333 Chemical Structure
BCP40415 RS67333 160845-95-4
RS-67333 is a 5-HT4R partial agonist that shows efficacy at 0.3 and 1.0 mg/kg, ip.
Tesofensine Chemical Structure
BCP37838 Tesofensine 402856-42-2
Tesofensine, an azabicyclo compound, has been found to be a 5-HT receptor inhibitor and could be used in the treatment of obesity.
GR 125743 Chemical Structure
BCP37767 GR 125743 148547-33-5
GR 125743 is a novel 5-HT1B/1D receptor antagonist.
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