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Chemical Structure Cat. No. Product Name CAS No.
Aurora Kinase Inhibitor II Chemical Structure
BCP48936 Aurora Kinase Inhibitor II 331770-21-9
Aurora Kinase Inhibitor II is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively.
SP-146 Chemical Structure
BCP48903 SP-146 2682114-54-9
SP-146 is a potent, selective and non-ATP-competitive inhibitor of Aurora B with IC50 of 0.316 nM. SP-146 can be used for the research of triple negative breast cancer (TNBC).
Aurora B inhibitor 1 Chemical Structure
BCP42843 Aurora B inhibitor 1 937276-52-3
Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.
SP-146 Chemical Structure
BCP35921 SP-146 SP-146
SP-146 is a potent, selective and non-ATP-competitive inhibitor of Aurora B with IC50 of 0.316 nM.
Phthalazinone pyrazole Chemical Structure
BCP33311 Phthalazinone pyrazole 880487-62-7
Phthalazinone pyrazole is a potent, selective and orally bioavailable inhibitor of Aurora-A kinase.
 Chemical Structure
Aurora Kinase Inhibitor III Chemical Structure
BCP30248 Aurora Kinase Inhibitor III 879127-16-9
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).
Cenisertib Chemical Structure
BCP28083 Cenisertib 871357-89-0
Cenisertib selectively binds to and inhibits aurora kinases (AKs), a family of serine-threonine kinases which are important regulators of cell division and proliferation, and which are overexpressed in certain types of cancer.
CCT241736 Chemical Structure
BCP29563 CCT241736 1402709-93-6
CCT241736 is a novel, orally bioavailable, imidazo[4,5-b]pyridine derivative discovered at our Institute, highly selective for FLT3 and Aurora kinases with an S(10) selectivity score using KINOMEscan™ technology of 0.057 (fraction of 386 non-mutant kinases inhibited >90% when screened at 1 uM of CCT241736; San Diego, CA).
AT9283 Chemical Structure
BCP11714 AT9283 896466-04-9
AT9283 is a multi-targeted inhibitor with IC50s of 1.2 nM, 1.1 nM for JAK2 and JAK3, respectively, and is also potent to Aurora A, Aurora B and Abl(T315I).
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