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Chemical Structure Cat. No. Product Name CAS No.
M-525 Chemical Structure
BCP46311 M-525 2173582-08-4
M-525 is a first-in-class, highly potent, irreversible small-molecule inhibitor of the menin-MLL interaction.
AZD4205 Chemical Structure
BCP46221 AZD4205 2091134-35-7
AZD4205 is a highly potent JAK1-selective kinase inhibitor with excellent preclinical pharmacokinetics with potential for further clinical development. JAK1 is part of the JAK1/signal transducer and activator of transcription (STAT) axis, which plays an important role in tumour escape from EGFR-targeted treatment.
Ifidancitinib Chemical Structure
BCP46085 Ifidancitinib 1236667-40-5
Ifidancitinib is a Janus kinase inhibitor.
MRTX1719 HCl Chemical Structure
BCP46040 MRTX1719 HCl MRTX1719HCl
MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells.
Ritlecitinib tosylate Chemical Structure
BCP45991 Ritlecitinib tosylate 2192215-81-7
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor.
Deuruxolitinib phosphate Chemical Structure
BCP45990 Deuruxolitinib phosphate 2147706-60-1
Deuruxolitinib(CTP-543), an oral inhibitor of Janus kinases JAK1 and JAK2, as a potential treatment for alopecia areata.
EZM0414 Chemical Structure
BCP45983 EZM0414 2411748-50-8
EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay).
dBRD9 Chemical Structure
BCP45901 dBRD9 2170679-45-3
dBRD9 is a potent and selective BRD9 bromodomain degrader composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide.
JQKD-82 Chemical Structure
BCP44757 JQKD-82 2410512-38-6
JQKD82, also known as PCK82, is a cell-permeable and selective KDM5 inhibitor (MM.1S cells, IC50 = 0.42 uM).
(R)-GSK-3685032 Chemical Structure
BCP45844 (R)-GSK-3685032 2170140-50-6
(R)-GSK-3685032 is the R-enantiomer of GSK-3685032.
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