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Cathepsin

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Cathepsin

Chemical Structure Cat. No. Product Name CAS No.
K-11777 Chemical Structure
 BCP48070 K-11777 233277-99-1
K-11777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively.
KGP94 Chemical Structure
 BCP46515 KGP94 1131456-28-4
KGP94 is cysteine protease Cathepsin L inhibitor(CTSL).
Papain Chemical Structure
 BCP44171 Papain 9001-73-4
Papain is a cysteine protease of the peptidase C1 family, which is used in food, pharmaceutical, textile, and cosmetic industries.
Z-PHE-PHE-FLUOROMETHYLKETONE Chemical Structure
 BCP40855 Z-PHE-PHE-FLUOROMETHYLKETONE 108005-94-3
Z-FF-FMK is a cell-permeant and irreversible inhibitor of cathepsin B and cathepsin L.
LHVS Chemical Structure
 BCP34916 LHVS 170111-28-1
LHVS is an irreversible cysteine protease cathepsin S (CatS) inhibitor.
CA-074 ME Chemical Structure
 BCP10805 CA-074 ME 147859-80-1
CA-074 methyl ester is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects.
Calpeptin Chemical Structure
 BCP34012 Calpeptin 117591-20-5
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets. Calpeptin is also an inhibitor of cathepsin K.
NSC 185058 Chemical Structure
 BCP30689 NSC 185058 39122-38-8
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. NSC185058 markedly attenuates autophagic activity.
Petesicatib Chemical Structure
 BCP30532 Petesicatib 1252637-35-6
Petesicatib is a cathepsin inhibitor drug candidate.
Z-Phe-Tyr(tBu)-diazomethylketone Chemical Structure
 BCP29942 Z-Phe-Tyr(tBu)-diazomethylketone 114014-15-2
Z-Phe-Tyr(tBu)-diazomethylketone is an irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.
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