Home   >  
Cell Cycle/DNA Damage

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products






Raw Materials


Chemical Structure Cat. No. Product Name CAS No.
Chk2 Inhibitor Chemical Structure
BCP46034 Chk2 Inhibitor 724708-21-8
Chk2 inhibitor is an inhibitor of checkpoint kinase 2 (Chk2).
Prexasertib mesylate Chemical Structure
BCP40573 Prexasertib mesylate 1234015-55-4
Prexasertib, also known as LY2606368, is a potent and selective Chk1/Chk2 inhibitor.
Prexasertib dimesylate Chemical Structure
BCP35489 Prexasertib dimesylate 1234015-58-7
Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM.
V158411 Chemical Structure
BCP25319 V158411 1174664-88-0
V158411 is a novel selective Chk1 inhibitor.
LY2880070 Chemical Structure
BCP32047 LY2880070 1375637-35-6
LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy. CHK1 is a serine/threonine kinase.
CCT241533 Chemical Structure
BCP21396 CCT241533 1262849-73-9
CCT241533 is a potent and selective Inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors.
GDC0575 hydrochloride Chemical Structure
BCP30767 GDC0575 hydrochloride 1196504-54-7
GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.
GDC-0575 dihydrochloride Chemical Structure
BCP29768 GDC-0575 dihydrochloride 1657014-42-0
GDC-0575 dihydrochloride is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
SAR-020106 Chemical Structure
BCP29578 SAR-020106 1184843-57-9
SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50 of 13.3 nM.
AZD7762 HCl Chemical Structure
BCP25387 AZD7762 HCl 1246094-78-9
AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and potentiating DNA-targeted therapies.
123下一页共 23 条记录 1 / 3 页