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Potassium Channel

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Potassium Channel

Chemical Structure Cat. No. Product Name CAS No.
Terfenadine Chemical Structure
 BCP43974 Terfenadine 50679-08-8
Terfenadine is a potent open-channel blocker of hERG with a mean IC50 of 204 nM.
A2793 Chemical Structure
 BCP42593 A2793 88349-90-0
A2793 is an efficient inhibitor of TWIK-related spinal cord potassium channel (TRESK, K2P18, KCNK18) and TASK-1 (KCNK3) with IC50 of 6.8 μM for mouse TRESK.
NS8593 hydrochloride Chemical Structure
 BCP41256 NS8593 hydrochloride 875755-24-1
NS8593 HCl is a selective KCa2 channel negative modulator.
ASP-2905 Chemical Structure
 BCP41250 ASP-2905 792184-90-8
ASP2905 is a potent and selective inhibitor of the potassium voltage-gated channel subfamily H member 3 (KCNH3).
NS 3623 Chemical Structure
 BCP40735 NS 3623 343630-41-1
NS 3623 is a KV11.1 (hERG) and KV4.3 channel activator. It can activate the IKr and Ito currents and display antiarrhythmic activity.
PD-118057 Chemical Structure
 BCP39203 PD-118057 313674-97-4
PD-118057 is a hERG channel enhancer. Human ether-a-go-go-related gene 1 (hERG1) K(+) channels mediate repolarization of cardiac action potentials.
BL-1249 Chemical Structure
 BCP39202 BL-1249 18200-13-0
BL-1249 is a selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channel activator.
XE 991 Chemical Structure
 BCP39201 XE 991 122955-42-4
XE991 is a potent and selective KCNQ channel blocker. XE991 blocks KCNQ2+3/M-currents (IC50 = 0.6-0.98 μM) and KCNQ1 homomeric channels (IC50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC50 = 11.1 μM).
MK-7145 Chemical Structure
 BCP38355 MK-7145 1255204-84-2
MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM.
Flupirtine Chemical Structure
 BCP38233 Flupirtine 56995-20-1
Flupirtine is a selective neuronal potassium channel opener act as an Analgesic, having substituted pyridine with central analgesic properties.
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