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Raw Materials
Potassium Channel
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP45728 | Vernakalant hydrochloride New | 748810-28-8 |
Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channelwt, Kv1.5 channelI508F, Kv1.5 channelT479A, respectively.
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BCP43974 | Terfenadine New | 50679-08-8 |
Terfenadine is a potent open-channel blocker of hERG with a mean IC50 of 204 nM.
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BCP42593 | A2793 New | 88349-90-0 |
A2793 is an efficient inhibitor of TWIK-related spinal cord potassium channel (TRESK, K2P18, KCNK18) and TASK-1 (KCNK3) with IC50 of 6.8 μM for mouse TRESK.
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BCP41256 | NS8593 hydrochloride New | 875755-24-1 |
NS8593 HCl is a selective KCa2 channel negative modulator.
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BCP41250 | ASP-2905 New | 792184-90-8 |
ASP2905 is a potent and selective inhibitor of the potassium voltage-gated channel subfamily H member 3 (KCNH3).
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BCP40735 | NS 3623 New | 343630-41-1 |
NS 3623 is a KV11.1 (hERG) and KV4.3 channel activator. It can activate the IKr and Ito currents and display antiarrhythmic activity.
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BCP39203 | PD-118057 New | 313674-97-4 |
PD-118057 is a hERG channel enhancer. Human ether-a-go-go-related gene 1 (hERG1) K(+) channels mediate repolarization of cardiac action potentials.
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BCP39202 | BL-1249 New | 18200-13-0 |
BL-1249 is a selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channel activator.
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BCP39201 | XE 991 New | 122955-42-4 |
XE991 is a potent and selective KCNQ channel blocker. XE991 blocks KCNQ2+3/M-currents (IC50 = 0.6-0.98 μM) and KCNQ1 homomeric channels (IC50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC50 = 11.1 μM).
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BCP38355 | MK-7145 New | 1255204-84-2 |
MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM.
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