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Carbonic Anhydrase

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Carbonic Anhydrase

Chemical Structure Cat. No. Product Name CAS No.
hCAIX-IN-5 Chemical Structure
 BCP49610 hCAIX-IN-5 2451479-57-3
hCAIX-IN-5 is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively.
Tioxolone Chemical Structure
 BCP27320 Tioxolone 4991-65-5
Tioxolone, a metalloenzyme carbonic anhydrase I inhibitor, is an anti-acne preparation.
Ethoxzolamide Chemical Structure
 BCP24088 Ethoxzolamide 452-35-7
Ethoxzolamide is a carbonic anhydrase inhibitor with Ki of 1 nM.
Disulfamide Chemical Structure
 BCP48058 Disulfamide 671-88-5
Disulfamide is a benzenedisulfonamide and carbonic anhydrase (CA) inhibitor with diuretic activity. Disulfamide inhibits CA, thereby preventing sodium, bicarbonate and thus water reabsorption in the proximal convoluted tubule resulting in diuresis.
CAIX Inhibitor S4 Chemical Structure
 BCP46833 CAIX Inhibitor S4 1330061-67-0
CAIX Inhibitor S4 is an inhibitor of carbonic anhydrase IX. It is selective for CAIX over CAI and CAII but does inhibit CAXII. It reduced the number of lung metastases, but not primary tumor growth, in an MDA-MB-231 mouse xenograft model.
Dorzolamide Chemical Structure
 BCP35353 Dorzolamide 120279-96-1
Dorzolamide is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.
Punicalin Chemical Structure
 BCP09702 Punicalin 65995-64-4
Punicalin is an ellagitannin.It is a highly active carbonic anhydrase inhibitor.
Sultiame Chemical Structure
 BCP30158 Sultiame 61-56-3
Sultiame is a carbonic anhydrase inhibitor used to treat epilepsy.
Indisulam Chemical Structure
 BCP06110 Indisulam 165668-41-7
Indisulam, also known as E7070, is a carbonic anhydrase inhbitor, is also a novel synthetic sulfonamide that targets the G1 phase of the cell cycle.
Dorzolomide hydrochloride Chemical Structure
 BCP21713 Dorzolomide hydrochloride 130693-82-2
Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.
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