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Ion Channel/Membrane Transporter
CRAC Channel

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CRAC Channel

Chemical Structure Cat. No. Product Name CAS No.
CRAC intermediate 2 Chemical Structure
BCP23922 CRAC intermediate 2 123066-64-8
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis, extracted from patent WO 2013059666A1.
GSK-5498A Chemical Structure
BCP23928 GSK-5498A 1253186-49-0
GSK-5498A is a selective small molecule blocker of CRAC channel(IC50=1 uM); inhibit mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
CM-4620 Chemical Structure
BCP29536 CM-4620 1713240-67-5
CM-4620 is a calcium-release activated calcium-channel (CRAC) inhibitor, with IC50s of 119, 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively.
YM-58483 Chemical Structure
BCP19298 YM-58483 223499-30-7
YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals.