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Chemical Structure Cat. No. Product Name CAS No.
Aloisine A Chemical Structure
BCP26893 Aloisine A 496864-16-5
Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3α (IC50: 500nM), GSK-3β (IC50: 650nM), JNK (IC50~3-10μM).
Edaglitazone Chemical Structure
BCP26908 Edaglitazone 213411-83-7
Edaglitazone is a PPARγ agonist potentially for the treatment of type 2 diabetes. Edarglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse.
Vindesine sulfate Chemical Structure
BCP28482 Vindesine sulfate 59917-39-4
Vindesine sulfate is an alkaloid sulfate salt. It has a role as an antineoplastic agent. It is functionally related to a vindesine.
DDD85646 Chemical Structure
BCP28646 DDD85646 1215010-55-1
DDD85646 is a potent inhibitor of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nm; hNMTIC50=4 nm). The enzyme N-myristoyltransferase (NMT) is a potential drug target for human African trypanosomiasis.
Ethaboxam Chemical Structure
BCP28799 Ethaboxam 162650-77-3
Ethaboxam is a β-tubulin inhibitor registered for the control of oomycete pathogens.
KU59403 Chemical Structure
BCP28847 KU59403 845932-30-1
KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively.
CCT244747 Chemical Structure
BCP23872 CCT244747 1404095-34-6
CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC50 of 7.7 nM; CCT244747 also abrogates G2 checkpoint with an IC50 of 29 nM.
AVN-944 Chemical Structure
BCP23877 AVN-944 297730-17-7
AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism, DNA replication, apoptosis and cell cycle control. AVN944 has been associated with cancer cell death in clinical trials. It is being investigated for the treatment of patients with advanced hematologic malignancies.
WD2000-012547 Chemical Structure
BCP24089 WD2000-012547 283172-68-9
WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221.
Voreloxin Hydrochloride Chemical Structure
BCP49069 Voreloxin Hydrochloride 175519-16-1
Voreloxin hydrochloride is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity.
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