Classified by application
All Products
Signaling Pathways
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- Epigenetics
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GPCR/G Protein
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Neuro Signaling Pathway
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Protease/Metabolic Enzyme
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Research Areas
- Metabolic Disease
- Neurological Disease
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- Diabetes
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- Allergy
- Infection
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Pyridazine Series
- Ammonia Series
- Amino acid
- Nucleoside Series
- Azaindazole
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrrole Series
- Boric acid
- Pyrimidine Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
Cell Cycle/DNA Damage
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP26893 | Aloisine A New | 496864-16-5 |
Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3α (IC50: 500nM), GSK-3β (IC50: 650nM), JNK (IC50~3-10μM).
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BCP26908 | Edaglitazone New | 213411-83-7 |
Edaglitazone is a PPARγ agonist potentially for the treatment of type 2 diabetes. Edarglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse.
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BCP28482 | Vindesine sulfate New | 59917-39-4 |
Vindesine sulfate is an alkaloid sulfate salt. It has a role as an antineoplastic agent. It is functionally related to a vindesine.
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BCP28646 | DDD85646 New | 1215010-55-1 |
DDD85646 is a potent inhibitor of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nm; hNMTIC50=4 nm). The enzyme N-myristoyltransferase (NMT) is a potential drug target for human African trypanosomiasis.
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BCP28799 | Ethaboxam New | 162650-77-3 |
Ethaboxam is a β-tubulin inhibitor registered for the control of oomycete pathogens.
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BCP28847 | KU59403 New | 845932-30-1 |
KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively.
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BCP23872 | CCT244747 New | 1404095-34-6 |
CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC50 of 7.7 nM; CCT244747 also abrogates G2 checkpoint with an IC50 of 29 nM.
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BCP23877 | AVN-944 New | 297730-17-7 |
AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism, DNA replication, apoptosis and cell cycle control. AVN944 has been associated with cancer cell death in clinical trials. It is being investigated for the treatment of patients with advanced hematologic malignancies.
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BCP24089 | WD2000-012547 New | 283172-68-9 |
WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221.
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BCP49069 | Voreloxin Hydrochloride New | 175519-16-1 |
Voreloxin hydrochloride is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity.
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