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All Products
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Neuro Signaling Pathway
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Protease/Metabolic Enzyme
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Research Areas
- Metabolic Disease
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Pyridazine Series
- Azaindazole
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrimidine Series
- Boric acid
- Pyrrole Series
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- Saccharide
- Azaindole
- Indole Series
- Indazole Series
- Piperidine Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
Cell Cycle/DNA Damage
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP46270 | CDK4/6-IN-6 New | 2380321-51-5 |
CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.
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BCP46265 | Bisantrene dihydrochloride New | 71439-68-4 |
Bisantrene Hydrochloride is the hydrochloride salt of an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the helical structure of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity.
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BCP46220 | CDK5-IN-3 New | 2639542-32-6 |
CDK5-IN-3 is a potent and selective CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively.
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BCP46219 | Zn-C3 New | 2376146-48-2 |
ZN-c3 is a highly selective Wee1 inhibitor (ICV50 = 3.8 nM) with balanced potency, ADME, and pharmacokinetic properties. ZN-c3 showed excellent in vivo efficacy and is currently being evaluated in phase 2 clinical trials.
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BCP41511 | DHODH-IN-16 New | 2511248-11-4 |
DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH.
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BCP46107 | Sovilnesib New | 2410796-79-9 |
Sovilnesibum is a kinesin-like protein KIF18A inhibitor.
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BCP46034 | Chk2 Inhibitor New | 724708-21-8 |
Chk2 inhibitor is an inhibitor of checkpoint kinase 2 (Chk2).
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BCP46030 | TH5427 New | 2253744-56-6 |
TH5427 is a potent, selective NUDT5 inhibitor (IC50=29 nM).
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BCP46015 | HSP27 inhibitor J2 New | 2133499-85-9 |
HSP27 inhibitor J2 is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function.
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BCP45963 | NPX800 New | 1693734-80-3 |
NPX-800 is a potent, selective, oral heat shock factor 1 (HSF1) pathway inhibitor.
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