奥曲肽
| CAS号 | 83150-76-9 | 货号 | BCP28870 |
| 中文名 | 奥曲肽 | ||
| 英文名 | Octreotide | ||
| 中文别名 | |||
| 英文别名 | Octreotide acetate; Longastatin; SMS-201-995; Octreotide-LAR; SMS 201-995; | ||
| 分子式 | C49H66N10O10S2 | 分子量 | 1019.24 |
| 生物活性 | Octreotide is a synthetic somatostatin analogue that resembles the native polypeptide in its activity in suppressing levels and activity of growth hormone, insulin, glucagon and many other gastrointestinal peptides. Because its half-life is longer than somatostatin, octreotide can be used clinically to treat neuroendocrine tumors that secrete excessive amounts of growth hormone (acromegaly) or other active hormones or neuropeptides. Octreotide has many side effects including suppression of gall bladder contractility and bile production, and maintenance therapy can cause cholelithiasis, pancreatitis as well as clinically apparent liver injury. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Somatostatin Receptor | ||
结构式
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