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GPCR/G Protein

结构式 货号 产品名称 CAS号
KRAS G12D inhibitor 5 结构式
BCP44856 KRAS G12D inhibitor 5 2621928-53-6
KRAS G12D inhibitor 5 is a KRAS G12D inhibitor for the potential treatment of pancreatic cancer.
RTICBM-189 结构式
BCP44866 RTICBM-189 551909-15-0
RTICBM-189 is a Urea derivative and a CB1 allosteric modulator.
Difelikefalin TFA 结构式
BCP44865 Difelikefalin TFA 2742623-88-5
Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM).
CCR3 Antagonist 结构式
BCP44858 CCR3 Antagonist 275812-32-3
KRAS G12D inhibitor 1 结构式
BCP43765 KRAS G12D inhibitor 1 2621928-43-4
KRAS G12D inhibitor 1 is a KRAS G12D inhibitor, with an IC50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation.
MRTX849 acid 结构式
BCP44575 MRTX849-溴丙酸衍生物 2561529-96-0
MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2.
MRTX849 analog 24 结构式
BCP44576 MRTX849 analog 24 2490716-96-4
MRTX849 analog 24 is an alkyne-containing click probe analogue of KRAS G12C inhibitor MRTX849, which is used to research MRTX849 function.
CL 316243 结构式
BCP44544 CL 316243 138908-40-4
CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors.CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.
U-54494A 结构式
BCP44497 U-54494A 92953-41-8
U-54494A is a κ-opioid agonist and a potential NMDA antagonist. U-54494A hydrochloride is used as an anticonvulsant.
Antazoline phosphate 结构式
BCP44465 安它唑啉磷酸酯 154-68-7
Antazoline phosphate is an antihistamine with anticholinergic properties used to relieve nasal congestion and the symptoms of allergic conjunctivitis. Antazoline is an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, and gastrointestinal and bronchial smooth muscles.
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