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Histone Methyltransferase

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Histone Methyltransferase

结构式 货号 产品名称 CAS号
AM-9747 结构式
BCP46595 AM-9747 2691869-82-4
AM-9747 is a MTA Cooperative PRMT5 Inhibitor.
MRTX1719 HCl 结构式
BCP46040 MRTX1719 HCl MRTX1719HCl
MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells.
EZM0414 结构式
BCP45983 EZM0414 2411748-50-8
EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay).
PF-06821497 结构式
BCP45826 PF-06821497 1844849-10-0
EZH2 Inhibitor PF-06821497 is an orally available selective inhibitor of the histone lysine methyltransferase (HMT) enhancer of zeste homolog 2 (EZH2), with potential antineoplastic activity.
PRMT5-IN-3 结构式
BCP45773 PRMT5-IN-3 2159123-14-3
PRMT5-IN-3 is a PRMT5 inhibitor that exhibits synthetic lethality to tumor cells but produce few side effects combined with DNA damaging agents.
BVT948 结构式
BCP45529 BVT948 39674-97-0
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor which can also inhibit several cytochrome P450 (P450) isoforms and lysine methyltransferase SETD8 (KMT5A).
UNC6934 结构式
BCP45445 UNC6934 2561494-77-5
UNC6934, a chemical probe targeting the PWWP domain, alters NSD2 nucleolar localization.
BAY-598 R-isomer 结构式
BCP44956 BAY-598 R-isomer 1906920-28-2
BAY-598 R-isomer is the R-isomer of BAY589.
SGC3027 结构式
BCP44921 SGC3027 2624313-13-7
SGC3027 is a histone methyltransferase inhibitor.
MRTX1719 结构式
BCP44551 MRTX1719 2630904-45-7
MRTX1719 is a first-in-class MTA-cooperative PRMT5 inhibitor that selectively elicits antitumor activity in MTAP/CDKN2A deleted cancer models
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