所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
- Motilin Receptor
- Glucose Transporter
- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Oxytocin Receptor
- Somatostatin Receptor
- Bradykinin Receptor
- Melanocortin Receptor
- Guanylate Cyclase
- Imidazoline Receptor
- PAR
- Neuropeptide Receptor
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Adenosine Receptor
- Glucagon Receptor
- Prostaglandin Receptor
- GnRH Receptor
- NK Receptor
- Glucocorticoid Receptor
- Leukotriene Receptor
- P2 Receptor
- mAChR
- CGRP Receptor
- GPR
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Vasopressin Receptor
- Smoothened/Smo
- mGluR
- Opioid Receptor
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- CGRP Receptor
- FAAH
- nAChR
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- Mitochondrial Metabolism
- Pyruvate Kinase
- SCD
- ALDH
- Serine Protease
- Neprilysin
- CETP
- FTase
- MLR
- MAGL
- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- Elastase
- NOX
- PAI1
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HCV Protease
- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Cytochrome P450
- Proteasome
- ACC
- Xanthine Oxidase
- Carboxypeptidase
- 11β HSD
- COMT
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Infection
- Inflammation
- Cancer
天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
MAPK Pathway
结构式 | 货号 | 产品名称 | CAS号 |
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BCP46470 | 布立匹肽 新 | 1445179-97-4 |
Brimapitide is a protease resistant, potent inhibitor specific for JNK (JNK1, JNK2 and JNK3).
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BCP46469 | MK2-IN-1hydrochloride 新 | 1314118-94-9 |
MK2-IN-1 hydrochloride is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.
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BCP46466 | PD184161 新 | 212631-67-9 |
PD184161 is an orally active MEK inhibitor. PD184161 inhibits MEK activity (IC50=10-100 nM) in a time- and concentration-dependent manner. PD184161 inhibits cell proliferation and induces apoptosis. PD184161 produces depressive-like behavior.
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BCP46452 | SM-7368 新 | 380623-76-7 |
SM-7368 inhibits TNF-alpha-induced MMP-9 upregulation in a concentration-dependent manner. SM-7368 strongly inhibits the TNF-alpha-induced invasion of HT1080 human fibrosarcoma cell line.
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BCP46296 | MNK1/2-IN-5 新 | 1426928-20-2 |
MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor as a therapeutic agent.
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BCP46274 | SB-747651A 新 | 607372-46-3 |
SB-747651A is a specific mitogen- and stress-activated kinase 1 (MSK1) inhibitor. SB-747651A can be used for the research of inflammation.
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BCP46273 | SB-747651A dihydrochloride 新 | 1781882-72-1 |
SB-747651A dihydrochloride is a potent MSK1 inhibitor; also inhibiting other AGC group kinases.
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BCP43532 | Zunsemetinib 新 | 1640282-42-3 |
Zunsemetinib, also knoiwn as ATI-450 and CDD450, is a potent MK2 Inhibitor. ATI-450 binds with high affinity to the interface of the p38MAPK-MK2 complex and selectively inhibits p38MAPK-catalysed phosphorylation of MK2 which stabilises the inactive conformation of MK2, and subsequently reduces inflammatory cytokine levels. ATI-450 specifically blocks the downstream MK2-mediated inflammatory drive on the p38 pathway and may therefore avoid the tachyphylaxis associated with p38 inhibitors.
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BCP45842 | PF-05381941 新 | 1474022-02-0 |
PF-05381941 is a novel potent dual TAK1/p38a inhibitor.
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BCP45765 | CMPD-1 新 | 41179-33-3 |
CMPD-1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with apparent Ki (Kiapp) of 330 nM.
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