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Estrogen Receptor

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Estrogen Receptor

结构式 货号 产品名称 CAS号
2-Hydroxyestrone 结构式
 BCP46743 2-羟雌甾酮 362-06-1
2-Hydroxyestrone, a specific receptor-mediated antiestrogenic agent with anticarcinogenic activity, inhibits the proliferation of estrogen receptor-positive MCF-7, but not estrogen receptor-negative MDA-MB-231.
ARV-471 结构式
 BCP45881 ARV-471 2229711-08-2
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader.
Amcenestrant 结构式
 BCP38455 Amcenestrant 2114339-57-8
Amcenestrant (SAR439859) is an orally available and nonsteroidal selective estrogen receptor degrader (SERD) with potential antineoplastic activity. SAR439859 is a potent estrogen receptor (ER) antagonist with EC50 of 0.2 nM for ERα degradation.
Giredestrant tartrate 结构式
 BCP43932 Giredestrant tartrate 2407529-33-1
Giredestrant, also known as GDC-9545 and RG6171, is a SERD.
E3 ligase Ligand 5 结构式
 BCP42856 E3 ligase Ligand 5 1055361-35-7
E3 ligase Ligand 5 is an estrogen-related receptor α (ERRα) antagonist with IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively.
PPT 结构式
 BCP41931 PPT 263717-53-9
PPT, also known as Propyl pyrazole triol, is an estrogen receptor (ERalpha) agonist. PPT also exerts anti-diabetic effects in mouse models.
Giredestrant 结构式
 BCP39883 Giredestrant 1953133-47-5
Giredestrant is a SERD.
trans-Clomifene Citrate 结构式
 BCP41267 反式-氯米芬柠檬酸盐 7599-79-3
trans-Clomiphene a non-steroidal estrogen receptor antagonist. It can be used for secondary hypogonadism in overweight men wishing to restore normal testicular function.
Clomifene 结构式
 BCP40562 氯米芬 911-45-5
Clomiphene is a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation.
Nafoxidine 结构式
 BCP39840 萘福昔定 1845-11-0
Nafoxidine is a member of naphthalenes, a ring assembly and a member of benzenes.
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