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Proton Pump

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Proton Pump

结构式 货号 产品名称 CAS号
Rohitukine 结构式
BCP44052 罗希吐碱 71294-60-5
Rohitukine is an anti-cancer agent. It acts through gastrin antagonism and H(+) K (+)-ATPase inhibition to modulate apoptosis pathways. Rohitukine ia an antidyslipidemic, antiadipogenic, gastroprotective, antifertility, and antileishmanial compound.
Pumaprazole 结构式
BCP43168 普马拉唑 158364-59-1
Pumaprazole is a potent, selective and reversible proton pump antagonist. Both before and after cure of H. pylori infection, pumaprazole raised the intragastric pH over a 24-h period to a similar degree as omeprazole. H. pylori infection similarly augments the pH-increasing effect of both drugs. This effect is related to H. pylori infection and not to an increased activation of acid inhibitory agents in the parietal cell compartment.
Tegoprazan 结构式
BCP38351 特戈拉赞 942195-55-3
Tegoprazan is a potassium-competitive acid blocker that controls gastric acid secretion and motility.
EN6 结构式
BCP34911 EN6 1808714-73-9
EN6 is a novel covalent autophagy activator targeting cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase which activates mTORC1 via the Rag guanosine triphosphatases.
(r)-Omeprazole 结构式
BCP21299 (R)-奥美拉唑 119141-89-8
(R)-omeprazole is a 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has R configuration at the sulfur atom. It is an enantiomer of an esomeprazole.
(R)-(+)-Pantoprazole magnesium salt 结构式
BCP20280 左旋泮托拉唑镁 657391-79-2
Pantoprazole is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
Concanamycin A 结构式
BCP21840 刀豆素A 80890-47-7
Concanamycin A is a specific inhibitor of V-type (vacuolar) H+-ATPase that displays > 2000-fold selectivity over other H+-ATPases (IC50 values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H+-ATPases and porcine P-type Na+,K+-ATPase respectively).
Ufiprazole 结构式
BCP21782 奥美拉唑硫醚 73590-85-9
Omeprazole sulfide is a metabolite of Omeprazole, which is a proton pump inhibitor.
Bedakillin 结构式
BCP21751 Bedakillin 654653-81-3
Bedakillin acts on the proton pump of the ATP-synthase enzyme , which is a different mechanism of action than for quinolones targeting DNA-gyrase .
Vonoprazan Fumarate 结构式
BCP13238 沃诺拉赞富马酸盐 881681-01-2
Vonoprazan is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.
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