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HMGCR

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HMGCR

结构式 货号 产品名称 CAS号
SR 12813 结构式
BCP25726 SR 12813 126411-39-0
SR12813 is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM.
Pravastatin 结构式
BCP21480 普伐他汀 81093-37-0
Pravastatin is a HMG-CoA Reductase Inhibitor. The mechanism of action of pravastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
Cerivastatin Sodium 结构式
BCP21297 西立伐他汀钠 143201-11-0
Cerivastatin Sodium is the sodium salt of cerivastatin, a synthetic lipid-lowering agent.
Cerivastatin 结构式
BCP24254 西立伐他汀 145599-86-6
Cerivastatin is a statins used to lower cholesterol and prevent cardiovascular disease. It was marketed by the pharmaceutical company Bayer A.G. in the late 1990s. Cerivastatin was voluntarily withdrawn from the market worldwide in 2001, due to reports of fatal rhabdomyolysis. During postmarketing surveillance, 52 deaths were reported in patients using Cerivastatin, mainly from rhabdomyolysis and its resultant renal failure.
Tert-butyl rosuvastatin 结构式
BCP13063 瑞舒伐他汀叔丁酯 355806-00-7
Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin a selective, competitive HMG-CoA reductase inhibitor.
Rosuvastatin sodium 结构式
BCP12749 瑞舒伐他汀钠 147098-18-8
Rosuvastatin Sodium Salt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase
Pitavastatin lactone 结构式
BCP11656 匹伐他汀内酯 141750-63-2
Pitavastatin (NK-104) is a potent HMG-CoA reductase inhibitor, Pitavastatin inhibited cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in a human liver cancer cell line (HepG2).
Clinofibrate 结构式
BCP13269 克利贝特 30299-08-2
Clinofibrate is a hypelipidemic agent and a HMG-CoA reductase inhibitor.
Pravastatin sodium 结构式
BCP13374 普伐他汀钠 81131-70-6
Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Mevastatin 结构式
BCP12101 美伐他汀 73573-88-3
Mevastatin (Compactin; ML236B) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans.
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