所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
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- Imidazoline Receptor
- PAR
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- Smoothened/Smo
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-
Neuro Signaling Pathway
- Imidazoline Receptor
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- FAAH
- nAChR
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- NFκB
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-
Protease/Metabolic Enzyme
- Mitochondrial Metabolism
- Pyruvate Kinase
- SCD
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- Serine Protease
- Neprilysin
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- FTase
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- E1 E2 E3 Enzyme
- Elastase
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- Phosphatase
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- Integrase
- Phosphodiesterase/PDE
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- ACC
- Xanthine Oxidase
- Carboxypeptidase
- 11β HSD
- COMT
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Infection
- Inflammation
- Cancer
天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
PDGFR
结构式 | 货号 | 产品名称 | CAS号 |
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BCP46277 | SU16F 新 | 251356-45-3 |
SU16F is a potent and selective platelet-derived growth factor receptor ß (PDGFRß) inhibitor.
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BCP44116 | SU4984 新 | 186610-89-9 |
SU4984 is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1 (FGFR1; IC50 = 10-20 µM).
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BCP37851 | PD089828 新 | 179343-17-0 |
PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC50s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC50=0.18 µM). PD-089828 also inhibits MAPK with an IC50 of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity.
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BCP34642 | CGP-53716 新 | 152459-94-4 |
CGP-53716 is a selective tyrosine kinase inhibitor of PDGFR.
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BCP30849 | Tyrosine kinase-IN-1 新 | 705946-27-6 |
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively.
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BCP14631 | 番泻苷 B 新 | 128-57-4 |
Sennoside B, a kind of irritant laxative isolated from rhei rhizome, inhibits PDGF-stimulated cell proliferation.
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BCP30695 | Masitinib Mesylate 新 | 1048007-93-7 |
Masitinib Mesylate is a potent and selective tyrosine kinase inhibitor that targets KIT.
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BCP30495 | 奥拉单抗 新 | 1024603-93-7 |
Olaratumab is a monoclonal antibody for the treatment of solid tumors.
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BCP30430 | Vorolanib 新 | 1013920-15-4 |
Vorolanib, also known as CM-082 and X-82, is small molecule dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) with antiangiogenic and antineoplastic activities.
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BCP20914 | N-Desethyl Sunitinib | 356068-97-8 |
N-Desethyl Sunitinib is a metabolite of sunitinib.
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